ArticleNature2023
PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
16.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 70 citations in OpenAlex.
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- A predictive model for immunotherapy efficacy in cancer based on dynamic changes of CD8+ T cells: a pan-cancer retrospective study.Frontiers in immunology · 2026Article
- Breast reconstructive considerations in patients at increased risk for radiodermatitis: combined checkpoint inhibitor and PARP inhibitor therapy.AME case reports · 2026Article
- Identification of Distinct Subtypes in Immune Tolerance after Hematopoietic Cell Transplantation Using the Prospective ABLE1.0 Pediatric Study Cohort.Transplantation and cellular therapy · 2026Article
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- Immune control of functional memory CD8 T cells in normal-appearing vitiligo skin.Science advances · 2025Article
- Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas.Cancer cell · 2025Article
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- Type 2 immunity links eczematous and lichenoid eruptions caused by immune checkpoint inhibitors.Journal of the American Academy of Dermatology · 2025Article
- CD8 T cells mediate immunosurveillance for neoantigen+ epithelial stem cells in the colon.bioRxiv : the preprint server for biology · 2025Article
- A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues.Nature immunology · 2025Article
Corrections and comments
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Authors and funding
18 authors at 1 institution in 1 country.
Martina DamoDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-7217-3221
Noah I HornickDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Aarthi VenkatDepartments of Genetics and of Computer Science, Yale University School of Medicine, New Haven, CT, USA.
Ivana WilliamDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Kathryn CluloDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Srividhya VenkatesanDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Jiaming HeDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-9494-3434
Eric FagerbergDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0313-3717
Jennifer L LozaDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-4200-394X
Darwin KwokDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Aya TalDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Jessica BuckDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Can CuiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-4736-4330
Jaiveer SinghDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
William E DamskyDepartment of Dermatology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0975-4071
Jonathan S LeventhalDepartment of Dermatology, Yale University School of Medicine, New Haven, CT, USA.
Smita KrishnaswamyDepartments of Genetics and of Computer Science, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-5823-1985
Nikhil S JoshiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. nikhil.joshi@yale.edu.ORCID 0000-0002-7045-7837
Yale University · US
Funding
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI MEGAN C KING · 1985 to 2026
$85.0MYale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0MYale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung CancerP50CA196530 · NCI · YALE UNIVERSITY · PI Kurt A Schalper · 2015 to 2026
$31.1MYale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI YASUKO IWAKIRI · 1986 to 2026
$31.1MYale Cancer Biology Training GrantT32CA193200 · NCI · YALE UNIVERSITY · PI PETER M GLAZER, Qin Yan · 2016 to 2026
$3.6MDeveloping translationally-relevant genetically engineered mouse models of lung adenocarcinoma for investigations in cancer immunologyR01CA237037 · NCI · YALE UNIVERSITY · PI JOSHI, NIKHIL · 2020 to 2024
$2.7MHuman and Translational Immunology Training ProgramT32AI155387 · NIAID · YALE UNIVERSITY · PI Joseph Edgar Craft, Kevan C Herold · 2021 to 2026
$2.6MFlow cytometer for high-parameter analysesS10OD026996 · OD · YALE UNIVERSITY · PI HABERMAN, ANN M · 2019 to 2019
$596kNCI NIH HHS P30 CA016359NCI NIH HHS P50 CA196530NCI NIH HHS R01 CA237037NCI NIH HHS T32 CA193200NIAID NIH HHS T32 AI155387NIDDK NIH HHS P30 DK034989NIDDK NIH HHS P30 DK045735NIH HHS S10 OD026996
Abstract
The peripheral T cell repertoire of healthy individuals contains self-reactive T cells
Indexed as
AntigensCD8-Positive T-LymphocytesImmune ToleranceProgrammed Cell Death 1 ReceptorSkinAnimalsBiopsyEpidermisGene Expression ProfilingHumansLichen PlanusMiceAntigensPDCD1 protein, humanPdcd1 protein, mouseProgrammed Cell Death 1 Receptor
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.