Evidence map›Paper›PMID 37344551›Full record

ReviewNature reviews. Microbiology2023

Prevention, treatment and cure of HIV infection.

Raphael J Landovitz, Hyman Scott, Steven G Deeks

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06250881 (Analysis of Ocular Complications of AIDS Patients in Ophthalmic Consultation), which is not on this map. Cited by 93 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06250881 unknown statusnot on this map

Analysis of Ocular Complications of AIDS Patients in Ophthalmic Consultation

TypeobservationalSponsorZhongnan HospitalRan2023 to 2024Enrolled500ConditionsOcular Complications in AIDS Patients, Such as Fundus Opportunistic Infections, Microangiopathy, and Uveitis
3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.

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  20. Prospective HIV RNA screening with long-acting cabotegravir pre-exposure prophylaxis in HPTN 083.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Raphael J LandovitzCenter for Clinical AIDS Research and Education, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1442-714X
Hyman ScottBridge HIV, San Francisco Department of Public Health, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-8775-7214
Steven G DeeksDivision of HIV, Infectious Diseases & Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA. Steven.Deeks@ucsf.edu.ORCID http://orcid.org/0000-0001-6371-747X
University of California, San Francisco · USAPLA Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of antiretroviral therapy for the prevention and treatment of HIV infection has been marked by a series of remarkable successes. However, the efforts to develop a vaccine have largely failed, and efforts to discover a cure are only now beginning to gain traction. In this Review, we describe recent progress on all fronts - pre-exposure prophylaxis, vaccines, treatment and cure - and we discuss the unmet needs, both current and in the coming years. We describe the emerging arsenal of drugs, biologics and strategies that will hopefully address these needs. Although HIV research has largely been siloed in the past, this is changing, as the emerging research agenda is marked by multiple cross-discipline synergies and collaborations. As the limitations of antiretroviral drugs as a means to truly end the epidemic are becoming more apparent, there is a great need for continued efforts to develop an effective preventative vaccine and a scalable cure, both of which remain formidable challenges.

Indexed as

HIV InfectionsHumans

Identifiers

PMID37344551
OpenAlexW4381480910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.