Evidence map›Paper›PMID 37344476›Full record

ArticleNature communications2023

Cyclic di-AMP traps proton-coupled K

Michael F Fuss, Jan-Philip Wieferig, Robin A Corey, Yvonne Hellmich, Igor Tascón, Joana S Sousa, Phillip J Stansfeld, Janet Vonck, Inga Hänelt

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. TheInfection and immunity · 2026
    Article
  2. Article
  3. Review
  4. Staying in the loop to make ends meet: roles and regulation of GlmR inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. The STING signaling pathways and bacterial infection.Apoptosis : an international journal on programmed cell death · 2025
    Review
  7. Bacterial cell volume regulation and the importance of cyclic di-AMP.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  8. c-di-AMP determines the hierarchical organization of bacterial RCK proteins.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Michael F Fuss *Institute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0002-8726-3131
Jan-Philip Wieferig *Department of Structural Biology, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.
Robin A Corey *Department of Biochemistry, University of Oxford, Oxford, UK.
Yvonne HellmichInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0002-5426-1551
Igor TascónInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0003-2526-6238
Joana S SousaDepartment of Structural Biology, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.
Phillip J StansfeldSchool of Life Sciences & Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.ORCID 0000-0001-8800-7669
Janet VonckDepartment of Structural Biology, Max Planck Institute of Biophysics, Frankfurt am Main, Germany. janet.vonck@biophys.mpg.de.ORCID 0000-0001-5659-8863
Inga HäneltInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany. haenelt@biochem.uni-frankfurt.de.ORCID 0000-0003-1495-3163
Goethe University Frankfurt · DEMax Planck Institute of Biophysics · DEIkerbasque · ESUniversity of Bristol · GBUniversity of Warwick · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P01948X/1Biotechnology and Biological Sciences Research Council BB/R002517/1Biotechnology and Biological Sciences Research Council BB/S003339/1Wellcome Trust
6 · The paper itself

Abstract

Cyclic di-AMP is the only known essential second messenger in bacteria and archaea, regulating different proteins indispensable for numerous physiological processes. In particular, it controls various potassium and osmolyte transporters involved in osmoregulation. In Bacillus subtilis, the K

Indexed as

Cyclic AMPProtonsBacterial ProteinsDinucleoside PhosphatesMembrane Transport ProteinsPotassiumSecond Messenger SystemsBacterial ProteinsCyclic AMPDinucleoside PhosphatesMembrane Transport ProteinsPotassiumProtons

Identifiers

PMID37344476
PMCPMC10284832
OpenAlexW4381548756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.