Evidence map›Paper›PMID 37344446›Full record

Trial reportJournal of atherosclerosis and thrombosis2023

Effects of Nutrition Education Program for the Japan Diet on Serum Phospholipid Fatty Acid Compositions in Patients with Dyslipidemia: Re-analysis of Data from a Previous Randomized Controlled Trial.

Chizuko Maruyama, Aisa Sato, Yui Nishikata, Mariko Nakazawa, Yuri Shijo, Noriko Kameyama, Ariko Umezawa, Makoto Ayaori, Masako Waki, Katsunori Ikewaki and 2 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of atherosclerosis and thrombosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chizuko MaruyamaDivision of Food and Nutrition, Graduate School of Human Sciences and Design, Japan Women's University.
Aisa SatoDivision of Food and Nutrition, Graduate School of Human Sciences and Design, Japan Women's University.
Yui NishikataDepartment of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University.
Mariko NakazawaDepartment of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University.
Yuri ShijoDivision of Food and Nutrition, Graduate School of Human Sciences and Design, Japan Women's University.
Noriko KameyamaDepartment of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University.
Ariko UmezawaDivision of Food and Nutrition, Graduate School of Human Sciences and Design, Japan Women's University.
Makoto AyaoriTokorozawa Heart Center.
Masako WakiShizuoka City Shizuoka Hospital.
Katsunori IkewakiDivision of Anti-aging, Department of Internal Medicine, National Defense Medical College.
Ai NishitaniTeikyo Academic Research Center, Teikyo University.
Tamio TeramotoTeikyo Academic Research Center, Teikyo University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe investigated changes in serum phospholipid fatty acid compositions with intake of the Japan Diet (JD) (higher consumption of fish, soybeans, vegetables, seaweed/mushrooms/konjak, and unrefined cereals with reduced consumption of animal fat, meat and poultry with fat, sweets and alcoholic drinks) recommended by the Japan Atherosclerosis Society.

methodsA randomized parallel controlled clinical trial on JD intake was conducted on Japanese patients with dyslipidemia. Nutrition education, based on the JD or partial JD (PJD) at baseline and at 3 months, was provided and the participants were followed up for 6 months. Fatty acids comprising serum phospholipids were measured in the JD (n=44) and PJD (n=44) groups.

resultsFatty acid intakes of C20:4, C20:5 and C22:6 increased in the JD group as compared with the PJD group. The percentages of serum phospholipid, C22:1 and C20:5 increased, while those of C18:1, C20:3(n-6) and C20:4(n-6) decreased in the JD as compared with the PJD group at 3 months. Changes in the phospholipid concentrations of C20:5, C22:5 and C22:6 reflected those intake volumes. Serum phospholipid C20:5 and C22:6 showed inverse correlations with C18:1, C18:2, and C20:3(n-6) at baseline and the changes at 3 and 6 months. In contrast, no correlation was observed between C20:4(n-6) and those n-3 fatty acids. The ratios of fatty acid concentrations, C16:1/C16:0 and C18:1/C18:0, decreased, but the ratio of C20:4(n-6)/C20:3(n-6) increased in the JD group.

conclusionNutrition education on the JD changed serum phospholipid fatty acid profiles in favor to prevent against cardiovascular risk factors in patients with dyslipidemia.

Indexed as

DyslipidemiasPhospholipidsAnimalsDietFatty AcidsHumansJapanFatty AcidsPhospholipidsDietDyslipidemiaFatty acidsJapaneseNutrition education

Identifiers

PMID37344446
PMCPMC10703566

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.