ArticleJournal of neurointerventional surgery2024
Optimal duration of dual antiplatelet therapy for stent-assisted coiling or flow diverter placement.
Article in Journal of neurointerventional surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Endovascular treatment of tumor-related dural sinus stenosis, venous outflow obstruction, and secondary intracranial hypertension: a systematic review of the literature.Journal of neuro-oncology · 2026Pooled it
- Endovascular management of internal carotid artery terminus aneurysms: a systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Efficacy and safety of flow diverters for the treatment of intracranial aneurysms: a systematic review and meta-analysis.Frontiers in surgery · 2026Pooled it
- Comparison of Stent-Assisted and Non-Stent-Assisted coil embolization in the treatment of Wide-Neck intracranial aneurysms: A Meta-Analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Comparative Analysis of Stent-Assisted Versus Non-Stent-Assisted Coiling in the Management of Ruptured Intracranial Aneurysms: A Systematic Review and Meta-Analysis.Translational stroke research · 2025Pooled it
- Treatment Algorithm for Concomitant Parasellar Meningiomas and Proximal Intracranial ICA Aneurysms in the Flow Diversion Era.Journal of neurological surgery. Part B, Skull base · 2026Article
- Understanding complication rates in elective endovascular aneurysm repair for consideration of same-day discharge.Neuroradiology · 2026Article
- Safety and hemodynamic efficacy of the LVIS stent in the endovascular treatment of intracranial wide-necked aneurysms: a single-center retrospective study.Chinese neurosurgical journal · 2026Article
- CYP2C19 genotype-guided antiplatelet therapy to prevent thromboembolic events after stent-assisted coil embolization of unruptured intracranial aneurysms: a retrospective cohort study.Journal of neurointerventional surgery · 2026Article
- MRA-based aneurysm occlusion assessment in the early phase after flow diverter treatment: a multicenter retrospective study focusing on the impact of aneurysm diameter.Neurosurgical review · 2026Article
- Associations of new intracranial haemorrhage, ischaemic stroke and survival with dual antiplatelet therapy regimen or duration after endovascular treatment for ruptured cerebral aneurysm.Stroke and vascular neurology · 2026Article
- Outcomes, complications, and management in flow diverter treatment of cerebral aneurysms: a 15-year single-center experience.Neuroradiology · 2026Article
- Overlapping Flow Diverter with Coiling for Fetal-type Posterior Communicating Artery Aneurysms with Triple Antithrombotic Therapy: A Case Series.NMC case report journal · 2026Article
- Perioperative Antiplatelet Therapy in the New Flow Diversion Era.Journal of neuroendovascular therapy · 2026Review
- Association of a platelet function testing-guided intensified antiplatelet strategy with thromboembolic events after EP2 stent-assisted coil embolization in patients with unruptured intracranial aneurysms.Frontiers in neurology · 2026Article
- Perianeurysmal edema after coil embolization of a giant ruptured aneurysm: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Comparative study of four platelet function tests conducted using two systems in neuroendovascular patients.Scientific reports · 2025Article
- Optimal duration of dual antiplatelet therapy after endovascular treatment of intracranial aneurysms with stenting: a systematic review and meta-analysis.Neuroradiology · 2025Review
- Microsurgical clipping of a recurrent anterior communicating artery aneurysm following WEB intrasaccular embolization: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Prediction and SHAP Analysis Integrating Morphological and Hemodynamic Parameters for Unruptured Intracranial Aneurysm Occlusion After Flow Diverter Treatment.CNS neuroscience & therapeutics · 2025Article
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDual antiplatelet therapy (DAPT) is necessary to prevent thromboembolic complications after stent-assisted coiling (SAC) or flow-diversion (FD) for cerebral aneurysms, but the optimal antiplatelet regimen remains unclear.
objectiveTo determine the optimal DAPT duration in patients with SAC/FD.
methodsThis multicenter cohort study enrolled patients who received SAC/FD for cerebral aneurysms at seven Japanese institutions between January 2010 and December 2020. The primary outcome was the time from procedure to the occurrence of a composite of target vessel-related thromboembolic events, procedure-unrelated major bleeding events, or death. The cumulative event-free survival rates were analyzed using a Kaplan-Meier curve, and the differences in each outcome between the groups dichotomized by the duration of DAPT were analyzed using the log-rank test.
resultsOf 632 patients (median observational period, 646 days), primary outcome occurred in 63 patients (10.0%), most frequently within 30 days after the procedure. The cumulative event-free survival rates at 30 days, 1 year, and 2 years after the procedure were 93.3% (91.4 to 95.3%), 91.5% (89.3 to 93.7%), and 89.5% (87.0 to 92.0%), respectively. The cumulative event-free survival rates after switching to monotherapy were similar for the >91 and <90 days DAPT groups in the population limited to patients who were switched from DAPT to monotherapy without major clinical events.
conclusionsThromboembolic events rarely occurred beyond 30 days after SAC/FD. The duration of DAPT may be shortened if patients have a periprocedural period without events. Further prospective studies are warranted to determine the optimal duration of antiplatelet therapy. TRIAL REGISTRATION NUMBER: UMIN000044122 :https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000050384.
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