Evidence map›Paper›PMID 37343559›Full record

ArticleCurrent biology : CB2023

Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation.

Sushila Ganguli, Tom Wyatt, Agata Nyga, Rachel H Lawson, Tim Meyer, Buzz Baum, Helen K Matthews

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Sushila GanguliLaboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK.
Tom WyattLaboratoirè Matiere et Systèmes Complexes, Université Paris Diderot, 10 rue Alice Domon et Léonie Duquet, Bâtiment Condorcet, 75013 Paris, France.
Agata NygaMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Rachel H LawsonSchool of Biosciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.
Tim MeyerUCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.
Buzz BaumLaboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address: bbaum@mrc-lmb.cam.ac.uk.
Helen K MatthewsLaboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK; School of Biosciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK. Electronic address: h.k.matthews@sheffield.ac.uk.
MRC Laboratory for Molecular Cell Biology · GBMRC Laboratory of Molecular Biology · GBUniversité Paris Cité · FRUniversity College London · GBUniversity of Sheffield · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R009732/1Cancer Research UK 5369923Cancer Research UK C1529/A17343Cancer Research UK C1529/A23335Medical Research Council MC_UP_1201/27Medical Research Council MR/X012077/1Wellcome Trust 222575Wellcome Trust 222575/Z/21/Z
6 · The paper itself

Abstract

Oncogenic Ras has been shown to change the way cancer cells divide by increasing the forces generated during mitotic rounding. In this way, Ras

Indexed as

ActomyosinMitosisActin CytoskeletonCell ProliferationGenes, rasSpindle ApparatusActomyosinactin cytoskeletoncell divisiondivision orientationfocal adhesionsMAPK signalingmitosismitotic roundingmitotic spindle

Identifiers

PMID37343559
PMCPMC7614879
OpenAlexW4381433195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.