ArticleBiomedical instrumentation & technology2023
Effects of Time, Temperature, and Humidity on Soil Drying on Medical Devices.
Article in Biomedical instrumentation & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum).Phytotherapy research : PTR · 2026Review
- Test Method Development for Cleaning Chemistry Performance Determination.Biomedical instrumentation & technology · 2025Article
- Chemical Changes Over Time Associated with Protein Drying.Biomedical instrumentation & technology · 2023Article
- Validation of the Device Feature Approach for Reusable Medical Device Cleaning Evaluations.Biomedical instrumentation & technology · 2023Article
- Test Soil and Material Affinity for Reusable Device Cleaning Validations.Biomedical instrumentation & technology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the healthcare environment, delays can occur that prevent reusable devices from being processed within the specified time outlined in manufacturers' instructions for use. It has been suggested in the literature and industry standards that residual soil components, such as proteins, may undergo a chemical change when they are exposed to heat or experience prolonged drying times under ambient conditions. However, little experimental data are available in the literature to document this change or how is may be addressed for cleaning efficacy. This study presents the effects of time and environmental conditions on contaminated instrumentation from the point of use until the cleaning process begins. It demonstrates that soil drying after a period of eight hours changes the solubility of the soil complex, with a significant change occurring after 72 hours. Temperature also contributes to chemical changes in protein. Although no significant difference occurred between 4°C and 22°C, temperatures greater than 22°C demonstrated a decrease in soil solubility in water. An increase in humidity prevented the soil from completely drying and prevented the chemical changes affecting solubility from occurring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.