Evidence map›Paper›PMID 37343064›Full record

ArticleOncotarget2023

Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability.

Shady I Tantawy, Natalia Timofeeva, Ana Hernandez, Aloke Sarkar, Varsha Gandhi

Abstract readEditorialComment
In one paragraph

Article in Oncotarget, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Shady I Tantawy
Natalia Timofeeva
Ana Hernandez
Aloke Sarkar
Varsha Gandhi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsApoptosisCell Line, TumorHumansMyeloid Cell Leukemia Sequence 1 ProteinProtein StabilityProto-Oncogene Proteins c-bcl-2Antineoplastic AgentsMyeloid Cell Leukemia Sequence 1 ProteinProto-Oncogene Proteins c-bcl-2AMG-176AZD5991B-cell leukemiaMCL-1 inhibitorMCL-1 protein

Identifiers

PMID37343064
PMCPMC10284423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.