ArticleFrontiers in neurology2023
The role of high-sensitivity C-reactive protein serum levels in the prognosis for patients with stroke: a meta-analysis.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- A Higher Burden of Abnormal Antioxidant-, Nutritional-, and Inflammation-Related Biomarkers Is Associated with Shoulder-Hand Syndrome, Hand Edema, and Short-Term Upper-Limb Outcomes During Stroke Rehabilitation.Antioxidants (Basel, Switzerland) · 2026Article
- Association of C-Reactive Protein with Functional Outcome After Acute Ischemic Stroke Across TOAST Subtypes.Journal of clinical medicine · 2026Article
- Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High-Sensitivity C-Reactive Protein Levels.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- The Prognostic Role of C-Reactive Protein-Triglyceride Glucose Index in Predicting Unfavorable Outcomes in Acute Ischemic Stroke: A Large-Scale Cohort Study.Brain and behavior · 2026Article
- Development and validation of a nomogram to predict early neurological deterioration in patients with acute ischemic stroke and type 2 diabetes mellitus: the pivotal role of glycemic variability and thrombo-inflammation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Microbiota, systemic immunity, and extracellular vesicles in stroke: peripheral nodes as therapeutic leverage points.Journal of neuroinflammation · 2026Review
- Association of a Composite Inflammatory Score with Stroke Prevalence: A Cross-Sectional Study.Life (Basel, Switzerland) · 2026Article
- Short-term trajectories of TyG-WHtR and hs-CRP and their joint impact on stroke risk in early CKM syndrome: evidence from Chinese national cohort.Scientific reports · 2026Article
- hs-CRP as a Marker of Systemic Low-Grade Inflammation Is Not Associated with Steatotic Liver Disease in Adolescents: Insights from the EVA4YOU Study.Metabolites · 2026Article
- Association between stress hyperglycemia ratio and early neurological deterioration after acute ischemic stroke: a retrospective cohort study.BMC neurology · 2026Article
- Admission Uric Acid, Troponin, and C-Reactive Protein Levels and In-Hospital Mortality in Acute Stroke Patients.International journal of general medicine · 2026Article
- Cumulative inflammatory, coagulation, and metabolic abnormalities predict poor 90-day functional outcome after endovascular thrombectomy for large-vessel occlusion acute ischemic stroke.Frontiers in neurology · 2026Article
- Comparative Prognostic Value of Baseline CRP, NLR, and MLR for 12-Month Outcomes After Ischaemic Stroke: A Prospective Cohort Study.Therapeutics and clinical risk management · 2026Article
- Serial immune-inflammatory recovery trajectories after acute ischemic stroke: associations with early neurological deterioration and 90-day functional outcome in a retrospective cohort.Frontiers in neurology · 2026Article
- A nomogram prediction model for 30-day mortality risk in severe cerebral infarction patients integrating inflammation-related indicators and APACHE II score.Frontiers in neurology · 2026Article
- Association of Endothelial Activation and Stress Index with Prognosis in Posterior Circulation Infarcts Treated with Recanalization Therapy.Diagnostics (Basel, Switzerland) · 2025Article
- Visceral Adiposity and Inflammation Index as Predictors of Stroke Risk in Middle and Older Age: A Cohort Study Across Blood Pressure Groups.Brain and behavior · 2025Article
- Serum Biomarkers in Acute Ischemic Stroke: Clinical Applications and Emerging Insights.Journal of clinical medicine · 2025Review
- Tracing Inflammation in Ischemic Stroke: Biomarkers and Clinical Insight.International journal of molecular sciences · 2025Review
- Predictive Value of C-Reactive Protein/Albumin Ratio (CAR) for Malnutrition and Sarcopenia in Acute Ischemic Stroke Patients.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The impact of high-sensitivity C-reactive protein (hs-CRP) as a biomarker of inflammation on the prognosis of stroke patients remains controversial, this study was conducted to evaluate the prognostic value of hs-CRP levels for patients with stroke. Methods: PubMed, Web of Science, Embase, and Cochrane Library databases were searched from inception to October 28, 2022. Outcome measures were all-cause mortality, recurrent stroke, and poor prognosis. The relationship between the highest versus lowest levels of hs-CRP or per unit increment and outcomes as measured by risk ratio (RR) and corresponding 95% confidence intervals (CI). Results: A total of 39 articles were eligible for meta-analysis. High hs-CRP levels at admission were associated with mortality among patients with acute ischemic stroke (AIS) [RR = 3.84, 95% CI (2.41 ~ 6.111); Conclusion: Hs-CRP levels are strongly associated with mortality, risk of stroke recurrence and poor prognosis in stroke patients. Therefore, hs-CRP levels may contribute to the prognosis prediction of these patients.
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