Evidence map›Paper›PMID 37342753›Full record

ArticleCureus2023

Model for End Stage Liver Disease (MELD) Score: A Tool for Prognosis and Prediction of Mortality in Patients With Decompensated Liver Cirrhosis.

Isioma Emenena, Bright Emenena, Anthony G Kweki, Henry O Aiwuyo, John O Osarenkhoe, Ugoeze N Iloeje, Nosakhare Ilerhunmwuwa, Beatrice E Torere, Oluwasegun Akinti, Adegboyega Akere and 1 more

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isioma EmenenaInternal Medicine/Gastroenterology, Delta State University Teaching Hospital, Oghara, NGA.
Bright EmenenaMedicine, BU Clinic/Hospital, Warri, NGA.
Anthony G KwekiInternal Medicine/Cardiology, Colchester Hospital, ESNEFT, Colchester, GBR.
Henry O AiwuyoInternal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.
John O OsarenkhoeMedicine and Surgery, Igbinedion University Teaching Hospital, Benin City, NGA.
Ugoeze N IloejeInternal Medicine/Cardiology, Federal Medical Centre, Yenagoa, NGA.
Nosakhare IlerhunmwuwaInternal Medicine, Brookdale Hospital Medical Center, Brooklyn, USA.
Beatrice E TorereInternal Medicine, North Mississippi Medical Center, Tupelo, USA.
Oluwasegun AkintiInternal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.
Adegboyega AkereMedicine, College of Medicine, University of Ibadan, Ibadan, NGA.
Omuemu E CasimirInternal Medicine, University of Benin, Benin City, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecompensated liver disease has become a common occurrence in medical wards. It has become the third most common cause of death in medical wards. This high mortality rate has become a matter of concern. It is important that a reliable scoring system helps to stratify patients with liver cirrhosis who will require liver transplantation.

objectiveTo determine the value of the Model for End-Stage Liver Disease (MELD) score in assessing the mortality of patients with decompensated liver cirrhosis over one month period (30 days). METHODS AND MATERIALS: A longitudinal study was conducted. A total of 110 patients diagnosed with decompensated liver cirrhosis were recruited from the gastroenterology clinic and medical wards of the University of Benin Teaching Hospital (UBTH), Benin City. The patients were recruited consecutively and met the inclusion criteria for the study. Demographic data, history, clinical, biochemical, ultrasonographic, and liver biopsy findings were evaluated in the patients who participated in this study.  Results: The mean age of the patients was 57 ± 11.06 years. Out of the 110 study participants, a 2.9:1 male-to-female ratio was appreciated in the patient population, with a total of 82 males and 28 females. Multiple logistic regression analysis identified MELD scores as an independent predictor of mortality in the studied patients. Predictive values of the MELD score for 1-month mortality which was analyzed using the receiver operating characteristic (ROC) curves showed that the MELD score had a sensitivity of 72.2% and positive predictive value of 93.6% with an area under the curve of 0.926 for all-cause mortality among decompensated liver cirrhosis patients.

conclusionMELD score is a good predictor of mortality among patients with decompensated liver cirrhosis over a 1-month (30 days) period.

Indexed as

cirrhosisdecompensated liver diseasemeld scoreprediction of mortalityprognosis

Identifiers

PMID37342753
PMCPMC10278970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.