ArticleBiomedical optics express2023
Non-invasive diffuse optical monitoring of cerebral physiology in an adult swine-model of impact traumatic brain injury.
Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Advances in Multimodality Monitoring in Traumatic Brain Injury.Current neurology and neuroscience reports · 2026Review
- Dose-dependent cerebral metabolic impairment in a swine model of carbon monoxide poisoning.Neurotoxicology · 2026Article
- Pre-Clinical Models of Traumatic Brain Injury-A Narrative Review Towards "Animal Neuro-ICUs".Biomedicines · 2026Review
- Optical and Microdialysis Monitoring of Succinate Prodrug Treatment in a Rotenone-Induced Model of Mitochondrial Dysfunction in Swine.Metabolites · 2026Article
- Sensing Through Tissues Using Diffuse Optical Imaging and Genetic Programming.Sensors (Basel, Switzerland) · 2026Article
- Attenuation of mitochondrial dysfunction in a ventricular fibrillation swine model of cardiac arrest treated with carbon monoxide.Resuscitation · 2025Article
- Establishing the feasibility and reliability of broadband absorption spectroscopy for measuring cerebral water content in adults.Biomedical optics express · 2025Article
- Unravelling Secondary Brain Injury: Insights from a Human-Sized Porcine Model of Acute Subdural Haematoma.Cells · 2024Article
- Introduction to the Optics and the Brain 2023 feature issue.Biomedical optics express · 2024Article
- Chassis-based fiber-coupled optical probe design for reproducible quantitative diffuse optical spectroscopy measurements.PloS one · 2024Article
- Comparison of diffuse correlation spectroscopy analytical models for measuring cerebral blood flow in adults.Journal of biomedical optics · 2023Article
Corrections and comments
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Authors and funding
21 authors at 2 institutions in 2 countries.
Funding
Abstract
In this study, we used diffuse optics to address the need for non-invasive, continuous monitoring of cerebral physiology following traumatic brain injury (TBI). We combined frequency-domain and broadband diffuse optical spectroscopy with diffuse correlation spectroscopy to monitor cerebral oxygen metabolism, cerebral blood volume, and cerebral water content in an established adult swine-model of impact TBI. Cerebral physiology was monitored before and after TBI (up to 14 days post injury). Overall, our results suggest that non-invasive optical monitoring can assess cerebral physiologic impairments post-TBI, including an initial reduction in oxygen metabolism, development of cerebral hemorrhage/hematoma, and brain swelling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.