Evidence map›Paper›PMID 37342689›Full record

ArticleBiomedical optics express2023

Raman spectromics method for fast and label-free genotype screening.

Shanshan Zhu, Yanjian Li, Fengdi Zhang, Changchun Xiong, Han Gao, Yudong Yao, Wei Qian, Chen Ding, Shuo Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shanshan ZhuResearch Institute of Medical and Biological Engineering, Ningbo University, Ningbo 315211, China.ORCID https://orcid.org/0000-0001-9265-8595
Yanjian LiCollege of Life and Health Sciences, Northeastern University, Shenyang 110169, China.
Fengdi ZhangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.
Changchun XiongCollege of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.
Han GaoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.
Yudong YaoResearch Institute of Medical and Biological Engineering, Ningbo University, Ningbo 315211, China.
Wei QianResearch Institute of Medical and Biological Engineering, Ningbo University, Ningbo 315211, China.
Chen DingCollege of Life and Health Sciences, Northeastern University, Shenyang 110169, China.
Shuo ChenCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.ORCID https://orcid.org/0000-0003-3893-715X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is now understood that genes and their various mutations are associated with the onset and progression of diseases. However, routine genetic testing techniques are limited by their high cost, time consumption, susceptibility to contamination, complex operation, and data analysis difficulties, rendering them unsuitable for genotype screening in many cases. Therefore, there is an urgent need to develop a rapid, sensitive, user-friendly, and cost-effective method for genotype screening and analysis. In this study, we propose and investigate a Raman spectroscopic method for achieving fast and label-free genotype screening. The method was validated using spontaneous Raman measurements of wild-type

Identifiers

PMID37342689
PMCPMC10278603

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.