ReviewFrontiers in veterinary science2023
Multiple uses of dexmedetomidine in small animals: a mini review.
Review in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Computed Tomographic Volumetric Analysis of the Nasal Cavities in Domestic Cats (Felis catus) and Anatomical Implications for Intranasal Drug Delivery.Anatomia, histologia, embryologia · 2026Article
- Anaesthetic Management Including Low-Dose Dexmedetomidine and Butorphanol in Dogs Undergoing ECG-Gated Cardiac Computed Tomography: A Retrospective Case Series.Veterinary sciences · 2026Article
- Interfascial Plane Blocks for Perioperative Analgesia in Dogs Undergoing Laparoscopic Ovariectomy: A Retrospective Study (2020-2025).Animals : an open access journal from MDPI · 2026Article
- Evaluation of the efficacy and safety of a modified anesthetic protocol using dexmedetomidine, midazolam, and butorphanol in mice.The Journal of veterinary medical science · 2026Article
- Perioperative analgesia and clinical safety of dexketoprofen in dogs undergoing ovariohysterectomy.Open veterinary journal · 2026Article
- Evaluation of a modified triple-combination anesthesia using dexmedetomidine in mice.Animal models and experimental medicine · 2025Article
- The locus coeruleus maintains core body temperature and protects against hypothermia during dexmedetomidine-induced sedation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dexmedetomidine induces immunogenic cancer cell death and sensitizes tumors to PD-1 blockade.Journal for immunotherapy of cancer · 2025Article
- Evaluation of different constant rate infusions of dexmedetomidine in cats undergoing elective surgery.Journal of feline medicine and surgery · 2025Article
- Effect of acepromazine or dexmedetomidine associated with methadone on anesthetic induction with propofol at a rate of 1 mg/kg/min in healthy dogs: A randomized clinical trial.Open veterinary journal · 2025Article
- Case report: Reconstruction with thyrohyoidopexy in a dog presented with complete laryngo-tracheal separation.Frontiers in veterinary science · 2025Article
- Tiletamine/Zolazepam and Ketamine with Dexmedetomidine (TKD) Cocktail Is as Effective as Tiletamine/Zolazepam and Ketamine with Xylazine (TKX) in Providing Pig General Anesthesia.Animals : an open access journal from MDPI · 2024Article
- Effect of dexmedetomidine constant rate infusion on the analgesic duration of peripheral nerve blocks in dogs: a randomized clinical study.Scientific reports · 2024Article
- Evaluation of the Quality of Recovery from General Anesthesia in Dogs with Two Different Low Doses of Dexmedetomidine.Animals : an open access journal from MDPI · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dexmedetomidine is an alpha-2 adrenergic agonist, which use had an exponential increase in human and veterinary medicine in the last 10 years. The aim of this mini review is to summarize the various uses of dexmedetomidine underlining its new applications and capabilities in the small animals' clinical activity. While this drug was born as sedative in veterinary medicine, some studies demonstrated to be effective as an analgesic both in single administration and in continuous infusion. Recent studies have also shown the role of dexmedetomidine as an adjuvant during locoregional anesthesia, increasing the duration of the sensitive block and consequently decreasing the demand for systemic analgesics. The various analgesic properties make dexmedetomidine an interesting drug for opioid-free analgesia. Some studies highlighted a potential neuroprotective, cardioprotective and vasculoprotective role of dexmedetomidine, thus conferring it a place in critical care medicine, such as trauma and septic patients. Dexmedetomidine has demonstrated to be a multitasking molecule and it is ready to face new challenges.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.