Evidence map›Paper›PMID 37342578›Full record

ArticleHeliyon2023

Study of hydrosalpinx on endometrial growth and expression of HOXA10mRNA and related factors.

Taolan Li, Fan Lu, Chengrong Wu, Yi Ling Cai, La Yang, Hualei Cai

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Taolan LiDepartment of Obstetrics and Gynecology, Guizhou Medical University, Guiyang, 550004, China.
Fan LuDepartment of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China.
Chengrong WuGuiyang Maternal and Child Health Care Hospital, Reproductive Center, Guiyang, 550004, China.
Yi Ling CaiBai Yun Hospital Affiliated to Guizhou Medical University, Department of Gynecology, Guiyang, 550004, China.
La YangDepartment of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China.
Hualei CaiDepartment of Obstetrics and Gynecology, Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China.
Guiyang Medical University · CNAffiliated Hospital of Guizhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of the study is to extract Methods: Once the extraction of the primary cells is over, the cells are cultured and other activities are performed such as the cell identification, CCK8 assay, cell decidua induction and HE staining. The researchers assessed the expression levels of HOXA10, IGFBP1 and avβ3 in either proliferation or secretion of the endometrium. This was accomplished using Western blot assay and real-time fluorescence quantitative PCR. Results: The results confirmed that at the time of endometrial proliferation, there was a decline in the expression of HOXA10 Conclusions: Among hydrosalpinx patients, one of the major mechanisms that damage the endometrium was found to be the abnormal expression of HOXA10 followed by IGFBP1 and avβ3, its downstream genes. This further results in the implantation of the embryo as well. Though it is possible to gradually repair the damage after the removal of hydrosalpinx, the recovery is a time-consuming process.

Indexed as

Endometrial receptivityHomeobox protein A10 (HOXA10)Human insulin-like growth factor-binding protein1 (IGFBP1)Hydrosalpinx fluid (HSF)Hydrosalpinx (HS)

Identifiers

PMID37342578
PMCPMC10277592
OpenAlexW4379740626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.