Evidence map›Paper›PMID 37342569›Full record

ArticleHeliyon2023

Understanding the viral shedding time of Omicron variant BA.2 infection in Shanghai: A population-based observational study.

Zhenzhen Lu, Zhongshu Kuang, Binzhe Li, Zhenju Song, Lihong Huang

Abstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhenzhen LuDepartment of Biostatistics, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.
Zhongshu KuangDepartment of Emergency Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.
Binzhe LiDepartment of Biostatistics, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.
Zhenju SongDepartment of Emergency Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.
Lihong HuangDepartment of Biostatistics, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To explore the multifactorial causality of prolonged viral shedding time and identify different viral shedding trajectories in Omicron BA.2 variant infections. Methods: The Kaplan-Meier method was used to estimate the survivor function, and the Cox proportional hazards model was fitted to identify factors associated with viral shedding time. Group-based trajectory model (GBTM) was used to identify different viral shedding trajectories. Ordinal logistic regression was used to identify factors that significantly impacted the trajectory membership. Results: The overall median viral shedding time was 12 days (interquartile range [IQR]: 8-15). Viral shedding time was longer for female cases, cases who were incompletely vaccinated, cases with comorbidities, cases with severe or critical infections and cases who had not taken Paxlovid within 5 days after diagnosis. Compared to the 3 to 17-year-old group, all older groups had significantly longer viral shedding times. The GBTMs based on the Conclusion: Increased age, comorbidities, incomplete vaccination, severe or critical infections, and delayed Paxlovid treatment were the risk factors for prolonged viral shedding time.

Indexed as

COVID-19Observational studySARS-CoV-2Viral shedding time

Identifiers

PMID37342569
PMCPMC10277587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.