Evidence map›Paper›PMID 37342347›Full record

ArticleFrontiers in immunology2023

Self-assembled albumin nanoparticles induce pyroptosis for photodynamic/photothermal/immuno synergistic therapies in triple-negative breast cancer.

Jianquan Yang, Wen Guo, Rong Huang, Jiaojiao Bian, Siqi Zhang, Ting Wei, Chuanshi He, Ziyue Hu, Juan Li, Chunyang Zhou and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

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  18. The Latest Look at PDT and Immune Checkpoints.Current issues in molecular biology · 2024
    Review
  19. Nanoparticle-Mediated Immunotherapy in Triple-Negative Breast Cancer.ACS biomaterials science & engineering · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jianquan YangSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Wen GuoInstitute of Materia Medica, North Sichuan Medical College, Nanchong, Sichuan, China.
Rong HuangInstitute of Materia Medica, North Sichuan Medical College, Nanchong, Sichuan, China.
Jiaojiao BianInstitute of Materia Medica, North Sichuan Medical College, Nanchong, Sichuan, China.
Siqi ZhangDepartment of Ultrasound Medical Center, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Ting WeiDepartment of Ultrasound Medical Center, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Chuanshi HeSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Ziyue HuDepartment of Ultrasound Medical Center, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Juan LiDepartment of Ultrasound Medical Center, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Chunyang ZhouInstitute of Materia Medica, North Sichuan Medical College, Nanchong, Sichuan, China.
Man LuSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
North Sichuan Medical University · CNUniversity of Electronic Science and Technology of China · CNSichuan Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is characterized by a high degree of malignancy, early metastasis, limited treatment, and poor prognosis. Immunotherapy, as a new and most promising treatment for cancer, has limited efficacy in TNBC because of the immunosuppressive tumor microenvironment (TME). Inducing pyroptosis and activating the cyclic guanosine monophosphate-adenosine monophosphate synthase/interferon gene stimulator (cGAS/STING) signaling pathway to upregulate innate immunity have become an emerging strategy for enhancing tumor immunotherapy. In this study, albumin nanospheres were constructed with photosensitizer-IR780 encapsulated in the core and cGAS-STING agonists/H

Indexed as

NanoparticlesPhotochemotherapyTriple Negative Breast NeoplasmsAlbuminsAnimalsHumansMicePyroptosisSulfidesTumor MicroenvironmentZinc CompoundsAlbuminsSulfidesZinc Compoundszinc sulfideimmunotherapynanomedicinephototherapypyroptosistriple-negative breast cancer

Identifiers

PMID37342347
PMCPMC10279487
OpenAlexW4378214279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.