Evidence map›Paper›PMID 37342343›Full record

ArticleFrontiers in immunology2023

Two tripartite classification systems of CD86

Guozeng Xu, Yuzhen Mo, Jing Li, Qingqing Wei, Fuxiang Zhou, Jian Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. PGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway.International journal of chronic obstructive pulmonary disease · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Guozeng XuDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Hubei, China.
Yuzhen MoDepartment of Radiation Oncology, Guangzhou Red Cross Hospital of Jinan University, Guangdong, China.
Jing LiDepartment of Oncology, Liuzhou People's Hospital of Guangxi Medical University, Guangxi, China.
Qingqing WeiDepartment of Oncology, Liuzhou People's Hospital of Guangxi Medical University, Guangxi, China.
Fuxiang ZhouDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Hubei, China.
Jian ChenDepartment of Medical Oncology, Yantai Yuhuangding Hospital of Qingdao University, Shandong, China.
Fourth Affiliated Hospital of Guangxi Medical University · CNJinan University · CNWuhan University · CNYuhuangding Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The prognostic value of tumor-associated macrophages remains unclear in colorectal cancer (CRC). Two tripartite classification systems, namely, ratio and quantity subgroups, were investigated as the prognostic stratification tools for stage II-III CRC. Methods: We assessed the infiltration intensity of CD86 Results: Ratio subgroups (RFS/OS: HR=2.677/2.708, all Conclusions: Ratio and quantity subgroups could serve as independent prognostic indicators that could potentially be incorporated into the tumor staging algorithm to improve prognostic stratification and provide better predictions of survival outcomes in stage II-III CRC after adjuvant chemotherapy.

Indexed as

Colorectal NeoplasmsNeoplasm Recurrence, LocalHumansMacrophagesNeoplasm StagingPrognosisCD206CD86colorectal cancermacrophage polarizationtripartite classification system

Identifiers

PMID37342343
PMCPMC10277500
OpenAlexW4379386536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.