Evidence map›Paper›PMID 37342232›Full record

ArticleFrontiers in cell and developmental biology2023

Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length.

Maciej Kliszczak, Daniela Moralli, Julia D Jankowska, Paulina Bryjka, Lamia Subha Meem, Tomas Goncalves, Svenja S Hester, Roman Fischer, David Clynes, Catherine M Green

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. GermlineInternational journal of molecular sciences · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maciej KliszczakNuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Daniela MoralliNuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Julia D JankowskaNuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Paulina BryjkaNuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Lamia Subha MeemNuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Tomas GoncalvesOncology Department, Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Svenja S HesterNuffield Department of Medicine, Target Discovery Institute, University of Oxford, Oxford, United Kingdom.
Roman FischerNuffield Department of Medicine, Target Discovery Institute, University of Oxford, Oxford, United Kingdom.
David ClynesOncology Department, Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Catherine M GreenNuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Centre for Human Genetics · GBUniversity of Oxford · GBChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary fibrosing poikiloderma (HFP) is a rare human dominant negative disorder caused by mutations in the

Indexed as

DNA damageFAM111BHFPlung fibrosisPOIKTMPproteasetelomeres

Identifiers

PMID37342232
PMCPMC10277729
OpenAlexW4379386504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.