Evidence map›Paper›PMID 37342113›Full record

ArticleLaryngoscope investigative otolaryngology2023

Treatment outcomes of mucosal melanoma of the head and neck: Analysis of 190 cases from a single institution.

Shu-Wei Chen, Meng-Hua Li, Jian-Liang Liu, Jing-Tao Chen, Jia Wang, Hui Li, Xi-Yuan Li, Ying Zhang, Ming Song, Jia-Xuan Lu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Mucosal Melanoma: An Overview of Recent Therapies.Current pharmaceutical design · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shu-Wei ChenDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Meng-Hua LiDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Jian-Liang LiuDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Jing-Tao ChenDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Jia WangDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Hui LiDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Xi-Yuan LiDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Ying ZhangDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.
Ming SongDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.ORCID https://orcid.org/0000-0001-7495-5895
Jia-Xuan LuDepartment of Pediatric Dentistry, Guanghua School of Stomatology, Affiliated Stomatological Hospital Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University Guangzhou Guangdong China.
Wen-Kuan ChenDepartment of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China.ORCID https://orcid.org/0000-0002-6825-3640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To analyze the treatment outcomes and prognostic factors of mucosal melanoma of the head and neck (MMHN) from a single institution. Methods: From December 1989 to November 2018, 190 patients diagnosed with MMHN were included. Survival analysis was performed using the Kaplan-Meier method for univariate analysis with a log-rank test for significance and Cox regression for multivariate analysis. Results: With a median follow-up time of 43.5 months, 126 (68.5%) patients died. The median DSS was 35 months. The 3- and 5-year disease-specific survival (DSS) rates were 48.1% and 33.7%, respectively. The median overall survival (OS) was 34 months. The 3- and 5-year OS rates were 47.0% and 32.9%, respectively. In univariate analysis, the T3 stage, received surgery, R0 resection, and combined therapy (surgery+biotherapy/biochemotherapy) were significantly associated with better survival. Multivariable Cox regression analysis revealed that the T4 stage (HR = 1.692; 95% CI, 1.175-2.438; Conclusion: The prognosis of MMHN remains poor. Systemic treatment is warranted to reduce MMHN progression. Surgery combined with biotherapy may improve survival.

Indexed as

biotherapyhead and neckmucosal melanomaprognosissurvivaltreatment

Identifiers

PMID37342113
PMCPMC10278118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.