Evidence map›Paper›PMID 37341895›Full record

ReviewJournal of thrombosis and thrombolysis2023

The risk of intracranial hemorrhage in glioma patients receiving anticoagulant treatment for venous thromboembolism: a bayesian network meta-analysis.

Huasong Huo, Shurui Shen, Yin Yang, Hongwei Zhang, Shouwang Wu, Taiyu Bi, Yunqian Li

Abstract readReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Review in Journal of thrombosis and thrombolysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huasong HuoDepartment of Neurosurgery, First Hospital of Jilin University, Changchun, China.
Shurui ShenDepartment of Plastic and Cosmetic Surgery, First Hospital of Jilin University, Changchun, China.
Yin YangDepartment of Hepatobiliary and Pancreatic Surgery, First Hospital of Jilin University, Changchun, China.
Hongwei ZhangDepartment of Gastrointestinal Colorectal and Anal Surgery, First Hospital of Jilin University, Changchun, China.
Shouwang WuDepartment of Urology, First Hospital of Jilin University, Changchun, China.
Taiyu BiDepartment of Thoracic Surgery, First Hospital of Jilin University, Changchun, China.
Yunqian LiDepartment of Neurosurgery, First Hospital of Jilin University, Changchun, China. yunqianli_jdyy@163.com.ORCID http://orcid.org/0000-0003-2199-8618
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to perform a Bayesian network meta-analysis to assess the risk of intracranial hemorrhage (ICH) in patients with glioma receiving anticoagulant treatment for venous thromboembolism.

methodsThe PubMed, Embase and Web of Science databases were searched for relevant publications until September 2022. All studies evaluating the risk of ICH in patients with glioma receiving anticoagulant treatment were included. Bayesian network meta-analysis and pairwise meta-analysis were performed to compare the ICH risk between the anticoagulant treatments. The Cochrane's Risk of Bias Tool and the Newcastle-Ottawa Scale (NOS) were used to evaluate the quality of studies.

resultsA total of 11 studies with 1301 patients were included. Pairwise comparisons showed no significant differences excepted with LMWH vs. DOACs (OR: 7.28, 95% CI: 2.11-25.17) and LMWH vs. Placebo (OR: 3.66, 95% CI: 2.15-6.24). For network meta-analysis, significant difference was found between patients treated with LMWH vs. Placebo (OR: 4.16, 95% CI: 2.00-10.14) and LMWH vs. DOACs (OR: 10.13, 95% CI: 2.70-70.19).

conclusionsIt seems that LMWH has the highest risk of ICH in glioma patients, while no evidence indicates that DOACs increase the risk of ICH. The use of DOACs may perhaps be a better choice. Further larger studies focusing on the benefit-to-risk ratio are warranted.

Indexed as

GliomaVenous ThromboembolismAnticoagulantsBayes TheoremHeparin, Low-Molecular-WeightHumansIntracranial HemorrhagesAnticoagulantsHeparin, Low-Molecular-WeightAnticoagulantsGliomaIntracranial hemorrhagesMeta-analysisThromboembolism

Identifiers

PMID37341895
OpenAlexW4381470014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.