Evidence map›Paper›PMID 37341758›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023

COVID-19-related secretory otitis media in the omicron era: a case series.

Yu Zhang, Jingrui Liu, Feifei Yang, Yanan He, Sinan Yan, Yushuang Bai, Zhanchi Zhang, Feng Luan

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yu Zhang *Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Jingrui Liu *Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Feifei YangDepartment of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Yanan HeDepartment of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Sinan YanDepartment of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Yushuang BaiDepartment of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Zhanchi ZhangDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, 050017, China. zhanchily@126.com.
Feng LuanDepartment of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China. luanfengly@163.com.ORCID http://orcid.org/0000-0003-1218-8461
Hebei Medical University · CN

Funding

Department of Health of Hebei Province 20220975Department of Health of Hebei Province 20221200Hebei Province Science and Technology Support Program 22377762D
6 · The paper itself

Abstract

objectivesIncreased numbers of patients with secretory otitis media appeared in outpatient clinics after the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron pandemic; however, the relationship between SARS-CoV-2 Omicron variant infection and secretory otitis media is uncertain.

methodsWe performed tympanocentesis and used reverse transcription-polymerase chain reaction (RT-PCR) testing to examine middle ear effusion (MEE) and nasopharyngeal secretions from 30 patients with secretory otitis media associated with SARS-CoV-2 infection. RT-PCR was performed using the open reading frame 1ab and nucleocapsid protein gene kit from Shanghai Berger Medical Technology Co., Ltd., as the sole assay method, in accordance with the manufacturer's instructions.

resultsMEEs from 5 of the 30 patients tested positive for SARS-CoV-2, including one patient with positive results for both the nasopharyngeal secretion and MEE. We report and discuss the medical records of six patients, including these five MEE-positive patients and a MEE-negative patient.

conclusionSARS-CoV-2 RNA can be detected in MEE caused by coronavirus disease 2019-related secretory otitis media even when a patient's nasopharyngeal secretion tests PCR-negative for SARS-CoV-2. The virus can remain in the MEE for a long time after SARS-CoV-2 infection.

Indexed as

COVID-19Otitis Media with EffusionChinaHumansRNA, ViralSARS-CoV-2RNA, ViralCOVID-19Middle ear effusionSARS-CoV-2 testSecretory otitis media

Identifiers

PMID37341758
OpenAlexW4381470569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.