Evidence map›Paper›PMID 37341426›Full record

ArticleEnvironmental science & technology2023

Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds.

Mohd Faheem Khan, Suvrat Chowdhary, Beate Koksch, Cormac D Murphy

Open access · hybridAbstract read
In one paragraph

Article in Environmental science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Complete genome sequence of fluoroacetate-degradingMicrobiology resource announcements · 2025
    Article
  10. Article
  11. Characteristics ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mohd Faheem KhanSchool of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.ORCID 0000-0002-0589-3368
Suvrat ChowdharyInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, Berlin 14195, Germany.
Beate KokschInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, Berlin 14195, Germany.ORCID 0000-0002-9747-0740
Cormac D MurphySchool of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.ORCID 0000-0002-2137-3338
Freie Universität Berlin · DEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three peptides comprising mono-, di-, and tri-fluoroethylglycine (MfeGly, DfeGly, and TfeGly) residues alternating with lysine were digested by readily available proteases (elastase, bromelain, trypsin, and proteinase K). The degree of degradation depended on the enzyme employed and the extent of fluorination. Incubation of the peptides with a microbial consortium from garden soil resulted in degradation, yielding fluoride ions. Further biodegradation studies conducted with the individual fluorinated amino acids demonstrated that the degree of defluorination followed the sequence MfeGly > DfeGly > TfeGly. Enrichment of the soil bacteria employing MfeGly as a sole carbon and energy source resulted in the isolation of a bacterium, which was identified as

Indexed as

BacteriaFluoridesBiodegradation, EnvironmentalFluoroacetatesPeptidesFluoridesFluoroacetatesPeptidesamino aciddehalogenasefluoroacetateorganofluorineprotease

Identifiers

PMID37341426
PMCPMC10324308
OpenAlexW4381469313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.