ArticleArquivos brasileiros de cardiologia2023
Fructose Consumption Alters Biogenic Amines Associated with Cardiovascular Disease Risk Factors.
Article in Arquivos brasileiros de cardiologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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13 authors at 1 institution in 1 country.
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Abstract
backgroundCardiovascular diseases (CVD) are the major cause of mortality worldwide, whose most prominent risk factor is unhealthy eating habits, such as high fructose intake. Biogenic amines (BAs) perform important functions in the human body. However, the effect of fructose consumption on BA levels is still unclear, as is the association between these and CVD risk factors.
objectiveThis study aimed to establish the association between BA levels and CVD risk factors in animals that consumed fructose.
methodsMale Wistar rats received standard chow (n=8) or standard chow + fructose in drinking water (30%) (n=8) over a 24-week period. At the end of this period, the nutritional and metabolic syndrome (MS) parameters and plasmatic BA levels were analyzed. A 5% level of significance was adopted.
resultsFructose consumption led to MS, reduced the levels of tryptophan and 5-hydroxitryptophan, and increased histamine. Tryptophan, histamine, and dopamine showed a correlation with metabolic syndrome parameters.
conclusionFructose consumption alters BAs associated with CVD risk factors.
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