Evidence map›Paper›PMID 37341203›Full record

ArticleRadiology and oncology2023

Quantitative dynamic contrast-enhanced parameters and intravoxel incoherent motion facilitate the prediction of TP53 status and risk stratification of early-stage endometrial carcinoma.

Hongxia Wang, Ruifang Yan, Zhong Li, Beiran Wang, Xingxing Jin, Zhenfang Guo, Wangyi Liu, Meng Zhang, Kaiyu Wang, Jinxia Guo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Radiology and oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hongxia WangDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Ruifang YanDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Zhong LiDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Beiran WangDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Xingxing JinDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Zhenfang GuoDepartment of Neurology, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Wangyi LiuDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Meng ZhangDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Kaiyu WangMR Research China, GE Healthcare, Beijing, China.
Jinxia GuoMR Research China, GE Healthcare, Beijing, China.
Dongming HanDepartment of MR, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
First Affiliated Hospital of Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to investigate the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and intravoxel incoherent motion (IVIM) in differentiating TP53-mutant from wild type, low-risk from non-low-risk early-stage endometrial carcinoma (EC). PATIENTS AND

methodsA total of 74 EC patients underwent pelvic MRI. Parameters volume transfer constant (K

resultsIn the TP53-mutant group, K

conclusionsBoth DCE-MRI and IVIM facilitate the prediction of TP53 status and risk stratification in early-stage EC. Compare with each single parameter, the combination of independent predictors provided better predictive power and may serve as a superior imaging marker.

Indexed as

Endometrial NeoplasmsFemaleHumansMagnetic Resonance ImagingMiddle AgedNeoplasm StagingRegression AnalysisRisk AssessmentTumor Suppressor Protein p53TP53 protein, humanTumor Suppressor Protein p53dynamic contrast-enhanced MRIearly-stage endometrial carcinomaintravoxel incoherent motionp53 statusrisk stratification

Identifiers

PMID37341203
PMCPMC10286889
OpenAlexW4381469434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.