Evidence map›Paper›PMID 37340719›Full record

ArticleThe Journal of international medical research2023

Pulmonary comorbidities in psoriasis are associated with a high risk of respiratory failure.

Kazuya Tanimura, Seyed Mehdi Nouraie, Divay Chandra, Toru Nyunoya

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Kazuya TanimuraDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0002-3406-9394
Seyed Mehdi NouraieDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Divay ChandraDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Toru NyunoyaDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0002-0688-4607
University of Pittsburgh · US

Funding

Role of FBXO24 mediated ubiquitination of FoxP1 protein in the pathogenesis and treatment of COPDR01HL153400 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHANDRA, DIVAY · 2020 to 2024
$2.3M
Role of TACC2 in smoking-induced COPDR01HL149719 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NYUNOYA, TORU · 2020 to 2023
$1.6M
Targeting F-box protein 048 in acute lung injuryI01CX000105 · VA · VETERANS HEALTH ADMINISTRATION · PI NYUNOYA, TORU · 2009 to 2022
–
CSRD VA I01 CX000105NHLBI NIH HHS R01 HL149719NHLBI NIH HHS R01 HL153400
6 · The paper itself

Abstract

objectivesTo identify respiratory comorbidities associated with a high risk of developing respiratory failure in subjects with psoriasis.

methodsThis was a cross-sectional analysis of data from subjects enrolled in the UK Biobank cohort. All diagnoses were self-reported. The risk of each respiratory comorbidity was compared by logistic regression models adjusting for age, sex, weight, diabetes mellitus, and smoking history; the risk of comorbid respiratory failure for each pulmonary comorbidity was also compared.

resultsOf the 472,782 Caucasian subjects in the database, 3,285 self-reported a diagnosis of psoriasis. More men and smokers reported psoriasis and were older, had higher weight and body mass index, and lower pulmonary function than non-psoriatic subjects. Those with psoriasis were at significantly higher risk for multiple pulmonary comorbidities compared to those without psoriasis. Furthermore, those with psoriasis had a higher risk for respiratory failure accompanied by asthma and airflow limitation than non-psoriatic subjects.

conclusionsSubjects with psoriasis and pulmonary comorbidities, such as asthma and airflow limitation, are at increased risk for respiratory failure. Common immunopathological links implicating a 'skin-lung axis' may underlie psoriasis and pulmonary comorbidities.

Indexed as

AsthmaPsoriasisRespiratory InsufficiencyComorbidityCross-Sectional StudiesHumansLungMaleRisk FactorspsoriasisPulmonary comorbiditiesrespiratory failure

Identifiers

PMID37340719
PMCPMC10288398
OpenAlexW4381469936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.