Evidence map›Paper›PMID 37340709›Full record

Observational studyDiabetes & vascular disease research

Glycemic control and outcome after carotid intervention in patients with T2D: A Swedish nationwide cohort study.

Alexander Zabala, Anders Gottsäter, Marcus Lind, Björn Eliasson, Rebecka Bertilsson, Jan Ekelund, Magnus Jonsson, Thomas Nyström

Open access · diamondAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Alexander ZabalaDepartment of Clinical Science and Education, Karolinska Institute, Södersjukhuset, Sweden.ORCID 0000-0001-5389-1271
Anders GottsäterDepartment of Clinical Sciences, Lund University, Malmö, Sweden.
Marcus LindDepartment of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Björn EliassonInstitute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Rebecka BertilssonCentre of Registers in Region Västra Götaland, Sweden.
Jan EkelundCentre of Registers in Region Västra Götaland, Sweden.
Magnus JonssonDepartment of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Thomas NyströmDepartment of Clinical Science and Education, Karolinska Institute, Södersjukhuset, Sweden.
Karolinska Institutet · SERegion Västra Götaland · SEKarolinska University Hospital · SELund University · SENU Hospital Group · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate the association between glycemic control and outcome in people with type 2 diabetes (T2D) after carotid intervention due to carotid stenosis.

methodsObservational nationwide population-based cohort study using inverse probability treatment weighting (IPTW) and Cox regressions with covariates, that is, 4 stepwise models, investigating the relationship between terciles of glycated hemoglobin (HbA1c) levels and stroke or death.

results1115 subjects with T2D undergoing carotid intervention were included during Jan 1st 2009 to Dec 31st 2015. Divided into terciles, with a mean HbA1c level of 44 (tercile 1), 53 (tercile 2), and 72 (tercile 3) mmol/mol. By using IPTW and Cox regression, each model was stepwise introduced for the investigating of relative risks, that is, hazard ratios (HRs) with associated 95% confidence intervals (CI). There was a significant increased risk for stroke or death, in every model observed for tercile 3, compared to tercile 1: HR for model 4: 1.35 (95% CI 1.02-1.78). No difference for stroke or death within 30 days was observed between the groups.

conclusionPoor glycemic control in people with T2D after carotid intervention is associated with an increased long-term risk for stroke or death.

Indexed as

Carotid StenosisDiabetes Mellitus, Type 2Endarterectomy, CarotidStrokeCohort StudiesGlycated HemoglobinGlycemic ControlHumansRisk FactorsSwedenTreatment OutcomeGlycated Hemoglobincarotid artery stentingcarotid endarterectomyCarotid stenosisglycemic controlstroketype 2 diabetes

Identifiers

PMID37340709
PMCPMC10286178
OpenAlexW4381470496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.