ArticleTransplantation2024
Racial and Ethnic Disparities in Liver Transplantation for Alcohol-associated Liver Diseases in the United States.
Article in Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Racial Disparities in Clinical and Cardiometabolic Outcomes Among Patients with Alcohol-Associated Liver Disease.Digestive diseases and sciences · 2026Article
- Disparities in Outcomes of Alcohol-Associated Hepatitis in the United States: Insights from the National Inpatient Sample, 2016-2022.Journal of racial and ethnic health disparities · 2026Article
- Trends and Demographics of Hepatorenal Syndrome-Related Mortality in the U.S., 1999-2024: A CDC WONDER Analysis.Diseases (Basel, Switzerland) · 2026Article
- Early liver transplantation in alcohol-associated liver disease-Evolution of practice, patient selection, management, and outcomes.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026Review
- Disparities in Liver Transplantation Among Native Americans and Hispanic Individuals: Insights from a Southwest Region Center in the United States of America.Journal of clinical medicine · 2026Article
- Racial and Ethnic Disparities in Outcomes in Liver Transplantation for Hepatocellular Carcinoma.The Journal of surgical research · 2026Article
- Albumin prevents kidney injury but is underutilized in a cohort of patients undergoing large-volume paracentesis.Hepatology communications · 2025Article
- Sex, racial, and ethnic disparities in United States liver transplantation clinical trials.World journal of hepatology · 2025Article
- Insights Into Liver Transplant Disparities.Gastroenterology & hepatology · 2025Article
- Opioid use after adult liver transplantation: Incidence, high-risk use, and adverse events in a large US cohort.Hepatology communications · 2025Article
- Alcohol-Associated Liver Disease Mortality.JAMA network open · 2025Article
- Liver Transplantation in Alcohol-Associated Liver Disease.Clinics in liver disease · 2025Review
- Metabolic dysfunction and alcohol-related liver disease (MetALD): Position statement by an expert panel on alcohol-related liver disease.Journal of hepatology · 2025Review
- Healthcare Contact Days Before and After Liver Transplant in Patients With Cirrhosis: A National Cohort Study.Clinical and translational gastroenterology · 2025Article
- Alcohol Use Disorder Medication Coverage and Utilization Management in Medicaid Managed Care Plans.JAMA network open · 2025Article
- A Comprehensive Assessment of Liver Transplant Trends and Outcomes Among Adults With Steatotic Liver Disease in the U.S.Gastro hep advances · 2025Article
- Disparities in steatosis prevalence in the United States by Race or Ethnicity according to the 2023 criteria.Communications medicine · 2024Article
- Disparities in Liver Transplant Outcomes: Race/Ethnicity and Individual- and Neighborhood-Level Socioeconomic Status.Clinical nursing research · 2024Article
- Racial Disparities in Alcoholic Hepatitis Hospitalizations in the United States: Trends, Outcomes, and Future Projections.Digestive diseases and sciences · 2024Article
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Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundEmerging data suggest disparities exist in liver transplantation (LT) for alcohol-associated liver disease (ALD). As the incidence of ALD increases, we aimed to characterize recent trends in ALD LT frequency and outcomes, including racial and ethnic disparities.
methodsUsing United Network for Organ Sharing/Organ Procurement and Transplantation Network data (2015 through 2021), we evaluated LT frequency, waitlist mortality, and graft survival among US adults with ALD (alcohol-associated hepatitis [AH] and alcohol-associated cirrhosis [AAC]) stratified by race and ethnicity. We used adjusted competing-risk regression analysis to evaluate waitlist outcomes, Kaplan-Meier analysis to illustrate graft survival, and Cox proportional hazards modeling to identify factors associated with graft survival.
resultsThere were 1211 AH and 26 526 AAC new LT waitlist additions, with 970 AH and 15 522 AAC LTs performed. Compared with non-Hispanic White patients (NHWs) with AAC, higher hazards of waitlist death were observed for Hispanic (subdistribution hazard ratio [SHR] = 1.23, 95% confidence interval [CI]: 1.16-1.32), Asian (SHR = 1.22, 95% CI:1. 01-1.47), and American Indian/Alaskan Native (SHR = 1.42, 95% CI: 1.15-1.76) candidates. Similarly, significantly higher graft failures were observed in non-Hispanic Black (HR = 1.32, 95% CI: 1.09-1.61) and American Indian/Alaskan Native (HR = 1.65, 95% CI: 1.15-2.38) patients with AAC than NHWs. We did not observe differences in waitlist or post-LT outcomes by race or ethnicity in AH, although analyses were limited by small subgroups.
conclusionsSignificant racial and ethnic disparities exist for ALD LT frequency and outcomes in the United States. Compared with NHWs, racial and ethnic minorities with AAC experience increased risk of waitlist mortality and graft failure. Efforts are needed to identify determinants for LT disparities in ALD that can inform intervention strategies.
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