Evidence map›Paper›PMID 37340378›Full record

ArticleBMC complementary medicine and therapies2023

Potential of methacrylated acemannan for exerting antioxidant-, cell proliferation-, and cell migration-inducing activities in vitro.

Meng-Han Chou, Yu-Hsu Chen, Ming-Te Cheng, Hung-Chi Chiang, Hou-Wen Chen, Ching-Wei Wang

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Meng-Han ChouGraduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan (ROC).
Yu-Hsu ChenDepartment of Orthopedic Surgery, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan (ROC).
Ming-Te ChengDepartment of Orthopedic Surgery, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan (ROC).
Hung-Chi ChiangDepartment of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan (ROC).
Hou-Wen Chen *Department of Emergency Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan (ROC). r0958169trueworld@gmail.com.
Ching-Wei Wang *Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan (ROC). cweiwang@mail.ntust.edu.tw.
National Taiwan University of Science and Technology · TWTao Yuan General Hospital · TWMinistry of Health and Welfare · KRNational Yang Ming Chiao Tung University · TW

Funding

Ministry of National Defense-Medical Affairs Bureau MND-MAB-110-054Ministry of Science and Technology of Taiwan 109-2221-E-011-018-MY3Taoyuan General Hospital, Ministry Health and Welfare PTH111075Tri-Service General Hospital ATSGH-C107-202; TSGH-C108-064; TSGH-D-109069
6 · The paper itself

Abstract

backgroundAcemannan is an acetylated polysaccharide of Aloe vera extract with antimicrobial, antitumor, antiviral, and antioxidant activities. This study aims to optimize the synthesis of acemannan from methacrylate powder using a simple method and characterize it for potential use as a wound-healing agent.

methodsAcemannan was purified from methacrylated acemannan and characterized using high-performance liquid chromatography (HPLC), Fourier-transform infrared spectroscopy (FTIR), and

resultsWe successfully optimized the synthesis of acemannan from methacrylate powder using a simple method. Our results demonstrated that methacrylated acemannan was identified as a polysaccharide with an acetylation degree similar to that in A. vera, with the FTIR revealing peaks at 1739.94 cm

conclusionOur study provides a suitable technique for effective acemannan production and presents acemannan as a potential agent for use in accelerating wound healing through its antioxidant properties, as well as cell proliferation- and migration-inducing activities.

Indexed as

AntioxidantsHydrogen PeroxideCell ProliferationMannansPolysaccharidesPowdersacemannanAntioxidantsHydrogen PeroxideMannansPolysaccharidesPowdersAcemannanAloe veraAntioxidantMigrationProliferationWound healing

Identifiers

PMID37340378
PMCPMC10283281
OpenAlexW4381435064

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.