Evidence map›Paper›PMID 37340168›Full record

SynthesisAging clinical and experimental research2023

Relationship between monounsaturated fatty acids and sarcopenia: a systematic review and meta-analysis of observational studies.

Sawan Ali, Graziamaria Corbi, Alessandro Medoro, Mariano Intrieri, Giovanni Scapagnini, Sergio Davinelli

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Prevention of Sarcopenia.Advances in experimental medicine and biology · 2025
    Review
  9. Review
  10. The role of dietary fats on cognition and sarcopenia in the elderly.Asia Pacific journal of clinical nutrition · 2024
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sawan AliDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Via De Sanctis 1, Campobasso, Italy.
Graziamaria CorbiDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Alessandro MedoroDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Via De Sanctis 1, Campobasso, Italy.
Mariano IntrieriDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Via De Sanctis 1, Campobasso, Italy.
Giovanni ScapagniniDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Via De Sanctis 1, Campobasso, Italy.
Sergio DavinelliDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Via De Sanctis 1, Campobasso, Italy. sergio.davinelli@unimol.it.ORCID http://orcid.org/0000-0003-2578-7199
University of Molise · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence suggests that fatty acids (FAs) play an essential role in regulating skeletal muscle mass and function throughout life. This systematic review and meta-analysis aimed to examine the relationship between dietary or circulatory levels of monounsaturated FAs (MUFAs) and sarcopenia in observational studies. A comprehensive literature search was performed in three databases (PubMed, Scopus, and Web of Science) from inception until August 2022. Of 414 records, a total of 12 observational studies were identified for this review. Ten studies were meta-analysed, comprising a total of 3704 participants. The results revealed that MUFA intake is inversely associated with sarcopenia (standardized mean difference = - 0.28, 95% CI - 0.46 to - 0.11; p < 0.01). Despite the limited number of studies, our results suggest that lower MUFA intake is associated with a higher risk of sarcopenia. However, the available evidence is still insufficient and further investigations are needed to demonstrate this relationship.

Indexed as

Fatty Acids, MonounsaturatedSarcopeniaDietFatty AcidsHumansObservational Studies as TopicFatty AcidsFatty Acids, MonounsaturatedMeta-analysisMonounsaturated fatty acidsMUFAObservational studySarcopenia

Identifiers

PMID37340168
PMCPMC10460305
OpenAlexW4381470475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.