ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Health-related quality of life profiles in adolescents and young adults with chronic conditions.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Association between chronic health problems and quality of life in medical students. Results of the POLLEK cohort study.Frontiers in public health · 2026Article
- Impact of hereditary angioedema attacks on health-related quality of life and work productivity.The World Allergy Organization journal · 2025Article
- Applying latent profile analysis to identify adolescents and young adults with chronic conditions at risk for poor health-related quality of life.Journal of biopharmaceutical statistics · 2025Article
- Health-related quality of life profiles of adults with arthritis and/or fibromyalgia: a cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo assess health-related quality of life (HRQOL) among adolescents and young adults (AYAs) with chronic conditions.
methodsAYAs (N = 872) aged 14-20 years completed NIH's Patient-Reported Outcomes Measurement Information System
resultsA 4-profile LPA model was selected. A total of 161 (18.5%), 256 (29.4%), 364 (41.7%), and 91 (10.4%) AYAs were classified into Minimal, Mild, Moderate, and Severe HRQOL Impact profiles. AYAs in each profile had distinctive mean scores with over a half standard deviation (5-points in PROMIS T-scores) of difference between profiles across most HRQOL domains. AYAs who were female or had conditions such as mental health condition, hypertension, and self-reported chronic pain were more likely to be in the Severe HRQOL Impact profile. The Huberty's I index was 0.36.
conclusionsApproximately half of AYAs with a chronic condition experience moderate to severe HRQOL impact. The availability of risk prediction models for HRQOL impact will help to identify AYAs who are in greatest need of closer clinical care follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.