Evidence map›Paper›PMID 37340024›Full record

ReviewCommunications biology2023

Paradoxical pharmacological dissociations result from drugs that enhance delta oscillations but preserve consciousness.

Joel Frohlich, Pedro A M Mediano, Francesco Bavato, Alireza Gharabaghi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Gamma-hydroxybutyrate to promote slow-wave sleep in major depressive disorder: a randomized crossover trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Joel FrohlichInstitute for Neuromodulation and Neurotechnology, University Hospital and University of Tuebingen, Tuebingen, Germany. jfneuro@pm.me.ORCID 0000-0001-8382-4344
Pedro A M MedianoDepartment of Computing, Imperial College London, London, UK.
Francesco BavatoExperimental and Clinical Pharmacopsychology, Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Alireza GharabaghiInstitute for Neuromodulation and Neurotechnology, University Hospital and University of Tuebingen, Tuebingen, Germany.
Hertie Institute for Clinical Brain Research · DEUniversity of Cambridge · GBUniversity of Tübingen · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-frequency (<4 Hz) neural activity, particularly in the delta band, is generally indicative of loss of consciousness and cortical down states, particularly when it is diffuse and high amplitude. Remarkably, however, drug challenge studies of several diverse classes of pharmacological agents-including drugs which treat epilepsy, activate GABA

Indexed as

ConsciousnessEpilepsyHumans

Identifiers

PMID37340024
PMCPMC10282051
OpenAlexW4381248153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.