Evidence map›Paper›PMID 37339967›Full record

ArticleNature communications2023

Structural basis of α

Yosuke Toyoda, Angqi Zhu, Fang Kong, Sisi Shan, Jiawei Zhao, Nan Wang, Xiaoou Sun, Linqi Zhang, Chuangye Yan, Brian K Kobilka and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 55 citations in OpenAlex.

  1. Corticosterone binds αHypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Antidepressant-Like Effects ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  10. Review
  11. Article
  12. Extracellular nanobody screening using conformationally stable GPCR variants.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. αPharmaceuticals (Basel, Switzerland) · 2025
    Review
  15. Review
  16. Review
  17. De novo design of a fusion protein tool for GPCR research.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Molecular mechanism of human αCommunications biology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Yosuke Toyoda *School of Medicine, Tsinghua University, Beijing, 100084, China. toyoda.yosuke.2r@kyoto-u.ac.jp.ORCID 0000-0002-2245-4666
Angqi Zhu *Beijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China.ORCID 0000-0002-3162-441X
Fang KongBeijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China.ORCID 0000-0001-8788-722X
Sisi ShanSchool of Medicine, Tsinghua University, Beijing, 100084, China.
Jiawei ZhaoSchool of Medicine, Tsinghua University, Beijing, 100084, China.
Nan WangBeijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China.
Xiaoou SunSchool of Medicine, Tsinghua University, Beijing, 100084, China.
Linqi ZhangSchool of Medicine, Tsinghua University, Beijing, 100084, China.
Chuangye YanBeijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China. yancy2019@mail.tsinghua.edu.cn.ORCID 0000-0001-9338-8048
Brian K KobilkaDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, 94305, USA. kobilka@stanford.edu.ORCID 0000-0001-5958-3990
Xiangyu LiuBeijing Frontier Research Center for Biological Structure, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China. liu_xy@mail.tsinghua.edu.cn.ORCID 0000-0003-3178-9238
Tsinghua University · CNCenter for Life Sciences · CNKing Center · USKyoto University · JPStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The α

Indexed as

OxymetazolineReceptors, Adrenergic, alpha-1Cryoelectron MicroscopyHumansNorepinephrineTamsulosinNorepinephrineOxymetazolineReceptors, Adrenergic, alpha-1Tamsulosin

Identifiers

PMID37339967
PMCPMC10282093
OpenAlexW4381433681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.