Evidence map›Paper›PMID 37339253›Full record

ArticleAnnals of work exposures and health2023

Chloroform exposure in air and water in Swedish indoor swimming pools-urine as a biomarker of occupational exposure.

Oskar Ragnebro, Kristin Helmersmo, Louise Fornander, Raymond Olsen, Ing-Liss Bryngelsson, Pål Graff, Jessica Westerlund

Open access · hybridAbstract read
In one paragraph

Article in Annals of work exposures and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Oskar RagnebroSchool of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
Kristin HelmersmoNational Institute of Occupational Health (STAMI), 0363 Oslo, Norway.
Louise FornanderDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.
Raymond OlsenNational Institute of Occupational Health (STAMI), 0363 Oslo, Norway.
Ing-Liss BryngelssonDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.
Pål GraffNational Institute of Occupational Health (STAMI), 0363 Oslo, Norway.ORCID 0000-0003-4928-617X
Jessica WesterlundDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.
Örebro University · SENational Institute of Occupational Health · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDisinfection by-products are produced in water disinfected with chlorine-based products. One such group is trihalomethanes, and chloroform is the most abundant trihalomethane in swimming pool areas. Chloroform can be absorbed by inhalation, ingestion, and dermal absorption, and is classified as possibly carcinogenic.

aimTo investigate if chloroform concentrations in air and water affect the chloroform concentration in urine samples of exposed swimming pool workers.

methodsWorkers from 5 adventure indoor swimming pools carried personal chloroform air samplers and provided up to 4 urine samples during one workday. Chloroform concentrations were analyzed with a linear mixed model analysis to investigate a possible correlation between air and urine concentrations.

resultsThe geometric mean chloroform concentration was 11 μg/m3 in air and 0.009 µg/g creatinine in urine among individuals with ≤2 h at work, 0.023 µg/g creatinine among those with >2-5 working hours, and 0.026 µg/g creatinine in the group with >5-10 working hours. A risk of higher levels of chloroform in urine was associated with longer hours at work (≤2 h versus >5-10 h, odds ratio [OR] 2.04, 95% confidence interval [CI] 1.25-3.34), personal chloroform concentrations in air (≤17.00 µg/m3 versus >28.00 µg/m3, OR 9.23, 95% CI 3.68-23.13) and working at least half the working day near the swimming pools (OR 3.16, 95% CI 1.33-7.55). Executing work tasks in the swimming pool water was not associated with higher chloroform concentrations in urine compared to only working on land (OR 0.82, 95% CI 0.27-2.45).

conclusionThere is an accumulation of chloroform concentrations in urine during a workday and a correlation between personal air and urine concentrations of chloroform among workers in Swedish indoor swimming pools.

Indexed as

Occupational ExposureSwimming PoolsBiomarkersChloroformCreatinineHumansSwedenTrihalomethanesBiomarkersChloroformCreatinineTrihalomethaneschloroformdisinfection by-productsexposure assessmentswimming poolstrihalomethanesurine

Identifiers

PMID37339253
PMCPMC10410492
OpenAlexW4381470644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.