Evidence map›Paper›PMID 37339230›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Dual factors required for cytochrome-P450-mediated hydrocarbon ring contraction in bacterial gibberellin phytohormone biosynthesis.

Raimund Nagel, Liza E Alexander, Charles E Stewart, Reuben J Peters

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. A nucleobase-driven P450 peroxidase system enables regio- and stereo-specific formation of C─C and C─N bonds.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raimund NagelRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011.ORCID 0000-0002-3878-7123
Liza E AlexanderRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011.ORCID 0000-0002-5244-8259
Charles E StewartMacromolecular X-ray Crystallography Facility, Iowa State University, Ames, IA 50011.
Reuben J PetersRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011.ORCID 0000-0003-4691-8477
Iowa State University · US

Funding

Purchase of replacement GC-MS for Peters R35/MIRA (GM131885)R35GM131885 · NIGMS · IOWA STATE UNIVERSITY · PI PETERS, REUBEN JOHN · 2019 to 2023
$2.6M
NIGMS NIH HHS R35 GM131885
6 · The paper itself

Abstract

Cytochromes P450 (CYPs) are heme-thiolate monooxygenases that prototypically catalyze the insertion of oxygen into unactivated C-H bonds but are capable of mediating more complex reactions. One of the most remarked-upon alternative reactions occurs during biosynthesis of the gibberellin A (GA) phytohormones, involving hydrocarbon ring contraction with coupled aldehyde extrusion of

Indexed as

GibberellinsPlant Growth RegulatorsBacteriaCatalysisCytochrome P-450 Enzyme SystemCytochrome P-450 Enzyme SystemGibberellinsPlant Growth Regulatorsenzymatic structure–functionmonooxygenasereaction mechanism

Identifiers

PMID37339230
PMCPMC10293830
OpenAlexW4381327539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.