Evidence map›Paper›PMID 37339228›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Contribution of the IGCR1 regulatory element and the 3'

Zhuoyi Liang, Lijuan Zhao, Adam Yongxin Ye, Sherry G Lin, Yiwen Zhang, Chunguang Guo, Hai-Qiang Dai, Zhaoqing Ba, Frederick W Alt

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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  5. Recurrent SARS-CoV-2 Omicron broadly neutralizing humanized antibodies in different single human VProceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhuoyi LiangHHMI, Boston Children's Hospital, Boston, MA 02115.
Lijuan ZhaoHHMI, Boston Children's Hospital, Boston, MA 02115.
Adam Yongxin YeHHMI, Boston Children's Hospital, Boston, MA 02115.
Sherry G LinHHMI, Boston Children's Hospital, Boston, MA 02115.
Yiwen ZhangHHMI, Boston Children's Hospital, Boston, MA 02115.
Chunguang GuoHHMI, Boston Children's Hospital, Boston, MA 02115.
Hai-Qiang DaiHHMI, Boston Children's Hospital, Boston, MA 02115.
Zhaoqing BaHHMI, Boston Children's Hospital, Boston, MA 02115.ORCID 0000-0002-8431-5469
Frederick W AltHHMI, Boston Children's Hospital, Boston, MA 02115.
Boston Children's Hospital · US

Funding

Mechanisms that Control IgH Variable Region Exon AssemblyR01AI020047 · NIAID · IMMUNE DISEASE INSTITUTE, INC. · PI ALT, FREDERICK W. · 1985 to 2025
$14.1M
Elucidating the role of cis-regulatory elements in mediating V(D)J recombinationF31AI117920 · NIAID · HARVARD MEDICAL SCHOOL · PI LIN, SHERRY GINGING · 2015 to 2017
$88k
NIAID NIH HHS F31 AI117920NIAID NIH HHS R01 AI020047
6 · The paper itself

Abstract

Immunoglobulin heavy chain variable region exons are assembled in progenitor-B cells, from V

Indexed as

Regulatory Sequences, Nucleic AcidV(D)J RecombinationAnimalsChromatinImmunoglobulin Variable RegionMicePrecursor Cells, B-LymphoidChromatinImmunoglobulin Variable Regionantibody repertoireschromatin 3D structureCTCFCTCF-binding elements (CBEs)V(D)J recombination

Identifiers

PMID37339228
PMCPMC10293834
OpenAlexW4381431913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.