Evidence map›Paper›PMID 37339210›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Pressure pushes tRNA

Jinqiu Wang, Tejaswi Koduru, Balasubramanian Harish, Scott A McCallum, Kevin P Larsen, Karishma S Patel, Edgar V Peters, Richard E Gillilan, Elisabetta V Puglisi, Joseph D Puglisi and 2 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jinqiu WangGraduate Program in Biochemistry and Biophysics, Rensselaer Polytechnic Institute, Troy, NY 12180.ORCID 0000-0001-5868-1935
Tejaswi KoduruDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180.ORCID 0000-0002-0055-9969
Balasubramanian HarishDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180.
Scott A McCallumCenter for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180.ORCID 0000-0002-6772-2150
Kevin P LarsenDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305.ORCID 0000-0002-3464-2023
Karishma S PatelDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305.ORCID 0000-0003-3034-3840
Edgar V PetersDepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, NY 12180.
Richard E GillilanCornell High Energy Synchrotron Source, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-7636-3188
Elisabetta V PuglisiDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305.
Joseph D PuglisiDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305.
George MakhatadzeDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180.ORCID 0000-0003-4565-1264
Catherine A RoyerDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180.ORCID 0000-0002-2670-3391
Rensselaer Polytechnic Institute · USStanford University · USCornell University · US

Funding

CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral DynamicsU54AI170856 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI WALTHER H MOTHES · 2022 to 2026
$34.4M
Training and OutreachP30GM124166 · NIGMS · CORNELL UNIVERSITY · PI RICHARD A. CERIONE · 2019 to 2026
$28.3M
Virus TransmissionP50AI150464 · NIAID · UNIVERSITY OF UTAH · PI SUNDQUIST, WESLEY I. · 2019 to 2021
$14.9M
NIAID NIH HHS P50 AI150464NIAID NIH HHS U54 AI170856NIGMS NIH HHS P30 GM124166
6 · The paper itself

Abstract

Conformational dynamics play essential roles in RNA function. However, detailed structural characterization of excited states of RNA remains challenging. Here, we apply high hydrostatic pressure (HP) to populate excited conformational states of tRNA

Indexed as

AnticodonRNANucleic Acid ConformationRNA, Transfer, LysScattering, Small AngleX-Ray DiffractionAnticodonRNARNA, Transfer, Lyshigh pressureMD simulationsNMRRNASAXS

Identifiers

PMID37339210
PMCPMC10293818
OpenAlexW4381327641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.