ArticleThe Journal of cell biology1986
Reactivation of organelle movements along the cytoskeletal framework of a giant freshwater ameba.
Article in The Journal of cell biology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 77 citations in OpenAlex.
- At the leading edge of three-dimensional cell migration.Journal of cell science · 2012Review
- Kinesin-3 and dynein cooperate in long-range retrograde endosome motility along a nonuniform microtubule array.Molecular biology of the cell · 2011Article
- A new perspective on microtubules and axon growth.The Journal of cell biology · 1993Review
- Subcellular distribution of the calcium-storing inositol 1,4,5-trisphosphate-sensitive organelle in rat liver. Possible linkage to the plasma membrane through the actin microfilaments.The Biochemical journal · 1991Article
- Nucleotide specificities of anterograde and retrograde organelle transport in Reticulomyxa are indistinguishable.The Journal of cell biology · 1991Article
- Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo.The Journal of cell biology · 1990Article
- Interactions of cytoplasmic granules with microtubules in human neutrophils.The Journal of cell biology · 1989Article
- Evidence for active interactions between microfilaments and microtubules in myxomycete flagellates.The Journal of cell biology · 1989Article
- Inhibition of surface membrane maturation in schistosomula of Schistosoma mansoni.Proceedings of the National Academy of Sciences of the United States of America · 1988Article
- Direction of force generated by the inner row of dynein arms on flagellar microtubules.The Journal of cell biology · 1987Article
- Accumulation of adrenocorticotropin secretory granules in the midbody of telophase AtT20 cells: evidence that secretory granules move anterogradely along microtubules.The Journal of cell biology · 1987Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The peripheral feeding network of the giant freshwater ameba Reticulomyxa can be easily and rapidly lysed to produce an extensive, stable, and completely exposed cytoskeletal framework of colinear microtubules and microfilaments. Most of the organelles that remain attached to this framework resume rapid saltatory movements at rates of up to 20 micron/s if ATP is added. This lysed model system is also capable of other forms of motility, namely an active splaying of microtubule bundles and bulk streaming. Reactivation does not occur with other nucleoside triphosphates, requires Mg ions, is insensitive to even high concentrations of erythro-9-(3-[2-hydroxynonyl]) adenine, is sensitive to vanadate only at concentrations of approximately 100 microM, and is inhibited by N-ethylmaleimide at concentrations greater than 100 microM. The physiology of this reactivation suggests an organelle transport motor distinct from cytoplasmic dynein and possibly the recently described kinesin. This system can serve as a model for elucidating the mechanisms of intracellular transport and, in addition, provides a unique opportunity to examine associations between microtubules and microfilaments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.