Evidence map›Paper›PMID 37338769›Full record

ArticleBulletin of experimental biology and medicine2023

Interaction of Graphene Oxide Nanoparticles with Human Mononuclear Cells in the Cell-IQ System.

S V Uzhviyuk, P V Khramtsov, M B Raev, V P Timganova, M S Bochkova, O G Khaziakhmatova, V V Malashchenko, L S Litvinova, S A Zamorina

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

S V UzhviyukInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia. kochurova.sofja@yandex.ru.
P V KhramtsovInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia.
M B RaevInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia.
V P TimganovaInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia.
M S BochkovaInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia.
O G KhaziakhmatovaInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia.
V V MalashchenkoI. Kant Baltic Federal University, Kaliningrad, Russia.
L S LitvinovaI. Kant Baltic Federal University, Kaliningrad, Russia.
S A ZamorinaInstitute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences - Branch of Perm State Research Center, Ural Division of the Russian Academy of Sciences, Perm, Russia.
Institute of Ecology and Genetics of Microorganisms · RUImmanuel Kant Baltic Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction of graphene oxide nanoparticles with human peripheral blood mononuclear cells was studied using the Cell-IQ continuous monitoring system for living cells. We used graphene oxide nanoparticles of various sizes coated with linear or branched polyethylene glycol (PEG) in concentrations of 5 and 25 μg/ml. After 24-h incubation with graphene oxide nanoparticles, the increase in the number of peripheral blood mononuclear cells at visualization points decreased; nanoparticles coated with branched PEG more markedly suppressed cell growth in culture. In the presence of graphene oxide nanoparticles, peripheral blood mononuclear cells retained high viability in culture after daily monitoring in the Cell-IQ system. The studied nanoparticles were engulfed by monocytes and the type of PEGylation had no effect on this process. Thus, graphene oxide nanoparticles reduced the increase in peripheral blood mononuclear cell mass during dynamic observation in the Cell-IQ system without reducing their viability.

Indexed as

GraphiteNanoparticlesHumansLeukocytes, MononuclearPolyethylene Glycolsgraphene oxideGraphitePolyethylene GlycolsCell-IQcell mass increasegraphene oxide nanoparticlespolyethylene glycolviability

Identifiers

PMID37338769
OpenAlexW4381308825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.