Evidence map›Paper›PMID 37338768›Full record

ArticleBulletin of experimental biology and medicine2023

B-Cell-Activating Factor Contributes to Elevation of the Content of Regulatory B Cells in Neonatal Sepsis.

W Liao, H Xiao, J He, L Huang, Y Liao, J Qin, Q Yang, F Ma, S Li

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Expansion of B10 cellsInternational journal of molecular medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

W LiaoDepartment of Pediatrics, Dongguan Houjie Hospital, Dongguan, China.
H XiaoDepartment of Pediatrics, Dongguan Houjie Hospital, Dongguan, China.
J HeDepartment of Pediatrics, Dongguan Houjie Hospital, Dongguan, China.
L HuangDepartment of Pediatrics, Dongguan Houjie Hospital, Dongguan, China.
Y LiaoDepartment of Pediatrics, Dongguan Houjie Hospital, Dongguan, China.
J QinDepartment of Pediatrics, Dongguan Houjie Hospital, Dongguan, China.
Q YangDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
F MaDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
S LiDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. lisit@mail.sysu.edu.cn.
Dongguan People’s Hospital · CNSixth Affiliated Hospital of Sun Yat-sen University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the role of B cell-activating factor (BAFF) in PI3K/AKT/mTOR signaling pathway in promoting proliferation and maintaining survival of regulatory B lymphocytes (Breg) in newborns with sepsis. The peripheral blood samples were collected from preterm neonates (n=40) diagnosed with sepsis on the day of diagnosis and on days 7, 14, and 21 after diagnosis, as well as from the matched preterm neonates without sepsis (n=40; control group). The peripheral blood mononuclear cells and B cells were isolated, cultured, and stimulated with LPS and immunostimulant CpG-oligodeoxynucleotide (CpG-ODN). Proliferation and differentiation of B-cells into CD19

Indexed as

B-Lymphocytes, RegulatoryNeonatal SepsisAntigens, CD19HumansInfant, NewbornInterleukin-4LipopolysaccharidesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesAntigens, CD19Interleukin-4LipopolysaccharidesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesB cell-activating factor (BAFF)neonatalPI3K/AKT/mTOR signaling pathwayregulatory B cellsepsis

Identifiers

PMID37338768
OpenAlexW4381308748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.