Evidence map›Paper›PMID 37338745›Full record

ReviewNano convergence2023

Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators.

Youngseop Lee, Hao F Zhang, Cheng Sun

Abstract readReview
In one paragraph

Review in Nano convergence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Youngseop LeeDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Cheng SunDepartment of Mechanical Engineering, Northwestern University, Evanston, IL, 60208, USA. c-sun@northwestern.edu.ORCID http://orcid.org/0000-0002-2744-0896

Funding

TR&D Project 3: Photoacoustic Detection of Metal Fluxes at the Tissue LevelP41GM135018 · NIGMS · NORTHWESTERN UNIVERSITY · PI JACOBSEN, CHRIS JOHNSON, O'HALLORAN, THOMAS V · 2020 to 2024
$5.8M
Photoactivatable Fluorophores for High-Throughput Multiplexed Tracking of Single-Molecules in Live CellsR01GM143397 · NIGMS · UNIVERSITY OF MIAMI CORAL GABLES · PI RAYMO, FRANCISCO M · 2022 to 2025
$1.4M
NIGMS NIH HHS P41 GM135018NIGMS NIH HHS P41GM135018NIGMS NIH HHS R01GM143397
6 · The paper itself

Abstract

Photoacoustic (PA) imaging enables noninvasive volumetric imaging of biological tissues by capturing the endogenous optical absorption contrast. Conventional ultrasound detectors using piezoelectric materials have been widely used for transducing ultrasound signals into the electrical signals for PA imaging reconstruction. However, their inherent limitations in detection bandwidth and sensitivity per unit area have unfortunately constrained the performance of PA imaging. Optical based ultrasound detection methods emerge to offer very promising solutions. In particular, polymer micro-ring resonators (MRRs) in the form of integrated photonic circuits (IPC) enable significant reduction for the sensing area to 80 μm in diameter, while maintaining highly sensitive ultrasound detection with noise equivalent pressure (NEP) of 0.49 Pa and a broad detection frequency range up to 250 MHz. The continued engineering innovation has further transformed MRRs to be transparent to the light and thus, opens up a wide range of applications, including multi-modality optical microscope with isometric resolution, PA endoscope, photoacoustic computed tomography (PACT), and more. This review article summarizes and discusses the evolution of polymer MRR design and the associated nanofabrication process for improving the performance of ultrasound detection. The resulting novel imaging applications will also be reviewed and discussed.

Indexed as

Maskless lithographyMicro-ring resonatorNano-fabricationNanoimprint lithographyPhotoacoustic imagingSoft nanoimprint lithographyUltrasound detector

Identifiers

PMID37338745
PMCPMC10281933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.