Evidence map›Paper›PMID 37338647›Full record

ArticleProtoplasma2023

Phytochemical screening, biological evaluation, anatomical, and morphological investigation of Ferula tingitana L. (Apiaceae).

Songül Karakaya, Hafize Yuca, Gülderen Yılmaz, Bilge Aydın, Enes Tekman, Gülnur Ekşi, Mehmet Bona, Gamze Göger, Mehmet Karadayı, Yusuf Gülşahin and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Protoplasma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Songül KarakayaDepartment of Pharmaceutical Botany, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey. snglkarakaya@yahoo.com.ORCID http://orcid.org/0000-0002-3268-721X
Hafize YucaDepartment of Pharmacognosy, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-0857-4776
Gülderen YılmazDepartment of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Ankara, Turkey.ORCID https://orcid.org/0000-0002-6569-4766
Bilge AydınDepartment of Pharmacognosy, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan, Turkey.ORCID https://orcid.org/0000-0002-7712-7259
Enes TekmanDepartment of Pharmaceutical Botany, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-1226-7218
Gülnur EkşiDepartment of Pharmacognosy, Faculty of Pharmacy, Medipol University, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-6869-8703
Mehmet BonaDepartment of Biology, Faculty of Science, İstanbul University, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-1656-2641
Gamze GögerDepartment of Pharmacognosy, Faculty of Pharmacy, Afyokarahisar Health Sciences University, Afyon, Turkey.ORCID https://orcid.org/0000-0003-2978-5385
Mehmet KaradayıDepartment of Biology, Faculty of Science, Atatürk University, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-2473-0409
Yusuf GülşahinInstitute of Natural and Applied Sciences, Atatürk University, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-3770-2116
Gözde ÖztürkDepartment of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0002-3998-8859
Betül DemirciDepartment of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0003-2343-746X
Zühal GüvenalpDepartment of Pharmacognosy, Faculty of Pharmacy, Atatürk University, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-8803-8147
Atatürk University · TRAnadolu University · TRAnkara University · TRErzincan Binali Yıldırım University · TRIstanbul Medipol University · TRIstanbul University · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferula tingitana L. is a high perennial plant and its leaf is an alternate arrangement and yellow, and its flowers are unisexual like other Apiaceae. It has been used as a spice and for various medicinal purposes in the Mediterranean region. The paper reports antidiabetic, antimicrobial, anticholinesterase, antioxidant, and genotoxic activities of leaves, flowers, stems, and fruits methanol extracts of F. tingitana. Also, quantitative determination of some secondary metabolites was also analyzed by LC-MS/MS. Moreover, chemical composition of essential oils was analyzed. Consequently, anatomical, and morphological properties of plant were investigated. Germacrene D (23.6%), 1,3,5-trimethylbenzene (18.4%), and α-pinene (50.0%) were found as the main compounds in flower, leaf, and stem oils, respectively. The cortex in stem, pedicel, and fruit is characterized by angular collenchyma cells and a distinct cambium layer. 6 compounds (quinic acid, fumaric acid, keracyanin chloride, cyanidin-3-O-glucoside, chlorogenic acid, hesperidin) were observed in samples. Leaf extract showed anticholinesterase activity. Leaf and flower extracts showed the highest % inhibition value on ABTS

Indexed as

FerulaPhytochemicalsPlant ExtractsAnti-Infective AgentsAntioxidantsCholinesterase InhibitorsFlowersOils, VolatilePlant LeavesAnti-Infective AgentsAntioxidantsCholinesterase InhibitorsOils, VolatilePhytochemicalsPlant ExtractsAnatomicalAnticholinesteraseAntidiabeticAntioxidantFerula tingitanaMorphological

Identifiers

PMID37338647
OpenAlexW4381309702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.