Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023
Technology-based supportive care for metastatic breast cancer patients.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04673019 (Nurse AMIE for Echo Show), which is not on this map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nurse AMIE for Echo Show: Randomized Control Trial
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Patient-Facing AI-Enabled Digital Health Technologies and Quality of Life in Cancer: Systematic Review and Exploratory Meta-Analysis.JMIR mHealth and uHealth · 2026Pooled it
- Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review.Journal of medical Internet research · 2025Pooled it
- The Effectiveness and Feasibility of Conversational Agents in Supporting Care for Patients With Cancer: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Using digital technology to support wellbeing and independence among people living with incurable cancers: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Response pathways and clinical workflow integration of digital symptom management platforms for breast cancer: A scoping review.Asia-Pacific journal of oncology nursing · 2026Review
- Adapting Nurse AMIE for rural oncology populations: A FRAME-guided analysis of a technology-enabled supportive care intervention.Contemporary clinical trials communications · 2026Article
- Artificial intelligence to meet the psychosocial needs of cancer patients: a systematic review of randomized controlled trials.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Physical activity interventions for women with metastatic breast cancer: a systematic review of published and ongoing randomised controlled trials.Journal of cancer survivorship : research and practice · 2025Review
- Conversational Agents to Support Pain Management: A Scoping Review.European journal of pain (London, England) · 2025Article
- AI Applications for Chronic Condition Self-Management: Scoping Review.Journal of medical Internet research · 2025Article
- Concordance with CONSORT-AI guidelines in reporting of randomised controlled trials investigating artificial intelligence in oncology: a systematic review.BMJ oncology · 2025Article
- Women with metastatic breast cancer don't just follow step-count trends, they exceed them: an exploratory study.Breast cancer research and treatment · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMetastatic breast cancer (MBC) patients are living longer. However, symptom burden remains a significant issue. Technology-based interventions may assist. The purpose of this study was to test a virtual assistant for addressing symptoms in MBC using the Amazon Echo Show with Alexa.
methodsIn this partial crossover randomized trial, the immediate treatment group was exposed to the intervention, called Nurse AMIE (Addressing Metastatic Individuals Everyday) for 6 months. The comparison group was unexposed for the first 3 months and then exposed for 3 months. The randomized controlled trial (RCT) during the first 3 months allowed for the evaluation of intervention effects on symptoms and function. The partial crossover maximized exposure to the intervention for evaluation of feasibility, usability, and satisfaction. RCT outcome data were collected at baseline and 3 months. Feasibility, usability, and satisfaction data were collected throughout the first 3 months of intervention exposure.
resultsForty-two MBC patients were randomized (1:1). Participants were 53 ± 11 years old and 4 ± 7 years from diagnosis with metastatic disease. No significant effects on psychosocial distress, pain, sleep disturbance, fatigue (vitality), quality of life, or chair stands were noted, despite high levels of acceptability (51%), feasibility (65%), and satisfaction (70%).
conclusionA high level of participant acceptability, feasibility, usability, and satisfaction all suggest further research on this platform is warranted. The lack of statistically significant effects on symptoms, quality of life, and function may be the result of small sample size. CLINICALTRIALS: GOV REGISTRATION NUMBER: NCT04673019 (registration date: December 17, 2020).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.