Evidence map›Paper›PMID 37338371›Full record

ArticleJournal of clinical microbiology2023

Escherichia coli ST131 Associated with Increased Mortality in Bloodstream Infections from Urinary Tract Source.

Amanda Brumwell, Granger Sutton, Paul M Lantos, Kate Hoffman, Felicia Ruffin, Lauren Brinkac, Thomas H Clarke, Mark D Adams, Vance G Fowler, Derrick E Fouts and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 16 citations in OpenAlex.

  1. Escherichia coli ST131 Drives Carbapenem Use for E. coli Bloodstream Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  2. Molecular characterization of extended-spectrum β-lactamases-producing Escherichia coli isolated from patients with bacteremia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  3. Loss of O-antigen due toScience advances · 2026
    Article
  4. Article
  5. Article
  6. Risk factors for antibiotic resistance and 30-day mortality among adult patients with acute leukemia and Escherichia coli bloodstream infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  7. Article
  8. Article
  9. High clonal diversity, resistome, and virulome ofFrontiers in microbiology · 2026
    Article
  10. Global High-RiskInternational journal of microbiology · 2026
    Article
  11. Infective endocarditis caused byThe Journal of international medical research · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Observational
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Amanda BrumwellDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Granger SuttonJ. Craig Venter Institute, Rockville, Maryland, USA.
Paul M LantosDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Kate HoffmanNicholas School of the Environment, Duke University, Durham, North Carolina, USA.
Felicia RuffinDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Lauren BrinkacJ. Craig Venter Institute, Rockville, Maryland, USA.
Thomas H ClarkeJ. Craig Venter Institute, Rockville, Maryland, USA.
Mark D AdamsJ. Craig Venter Institute, Rockville, Maryland, USA.ORCID 0000-0003-3161-7460
Vance G FowlerDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Derrick E FoutsJ. Craig Venter Institute, Rockville, Maryland, USA.ORCID 0000-0003-4323-7668
Joshua T ThadenDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-3250-0697
Duke University · USJ. Craig Venter Institute · US

Funding

The J. Craig Venter Institute Genome Center for Infectious DiseasesU19AI110819 · NIAID · J. CRAIG VENTER INSTITUTE, INC. · PI TAN, GENE · 2014 to 2018
$29.7M
HLA Fine Mapping to Elucidate S. aureus SusceptibilityR01AI165671 · NIAID · DUKE UNIVERSITY · PI FOWLER, VANCE G., SCOTT, WILLIAM K · 2021 to 2025
$3.8M
Characterization of a Novel E. coli Type III Secretion System Associated with Increased Patient MortalityK08AI171183 · NIAID · DUKE UNIVERSITY · PI Joshua T Thaden · 2022 to 2026
$895k
NCEZID CDC HHS U54 CK000603NIAID NIH HHS K08 AI171183NIAID NIH HHS R01 AI165671NIAID NIH HHS U19 AI110819
6 · The paper itself

Abstract

Escherichia coli sequence type 131 (ST131) is a globally dominant multidrug-resistant clone, although its clinical impact on patients with bloodstream infection (BSI) is incompletely understood. This study aims to further define the risk factors, clinical outcomes, and bacterial genetics associated with ST131 BSI. A prospectively enrolled cohort study of adult inpatients with E. coli BSI was conducted from 2002 to 2015. Whole-genome sequencing was performed with the E. coli isolates. Of the 227 patients with E. coli BSI in this study, 88 (39%) were infected with ST131. Patients with E. coli ST131 BSI and those with non-ST131 BSI did not differ with respect to in-hospital mortality (17/82 [20%] versus 26/145 [18%];

Indexed as

Escherichia coli InfectionsSepsisUrinary TractUrinary Tract InfectionsAdultAnti-Bacterial Agentsbeta-LactamasesCohort StudiesEscherichia coliHumansAnti-Bacterial Agentsbeta-Lactamasesbacteremiabloodstream infectionsEscherichia coliST131urinary tract infection

Identifiers

PMID37338371
PMCPMC10358158
OpenAlexW4381309891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.