Evidence map›Paper›PMID 37338301›Full record

ArticleGenetics and molecular biology2023

The SARS-CoV-2 mutation landscape is shaped before replication starts.

Diego Masone, Maria Soledad Alvarez, Luis Mariano Polo

Abstract read
In one paragraph

Article in Genetics and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Diego MasoneConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo (UNCuyo), Instituto de Histología y Embriología de Mendoza (IHEM), Mendoza, Argentina.ORCID 0000-0001-5770-8614
Maria Soledad AlvarezConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo (UNCuyo), Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Mendoza, Argentina.ORCID 0000-0001-7062-014X
Luis Mariano PoloConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Cuyo (UNCuyo), Instituto de Histología y Embriología de Mendoza (IHEM), Mendoza, Argentina.ORCID 0000-0001-9257-6127

Funding

DEVELOPMENT OF NATIONAL INFLUENZA SENTINEL SURVEILLANCE SYSTEM IN VIETNAMU51IP000409 · IP · NATIONAL INSTITUTE HYGIENE/EPIDEMIOLOGY · PI HIEN, NGUYEN TRAN · 2010 to 2015
$1.6M
NCIRD CDC HHS U51 IP000409
6 · The paper itself

Abstract

Mutation landscapes and signatures have been thoroughly studied in SARS-CoV-2. Here, we analyse those patterns and link their changes to the viral replication tissue in the respiratory tract. Surprisingly, a substantial difference in those patterns is observed in samples from vaccinated patients. Hence, we propose a model to explain where those mutations could originate during the replication cycle.

Identifiers

PMID37338301
PMCPMC10280802

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.