Evidence map›Paper›PMID 37338289›Full record

ReviewMolecular pharmaceutics2023

Oxygenated Wound Dressings for Hypoxia Mitigation and Enhanced Wound Healing.

Xiaoxue Han, Leah Suyeon Ju, Joseph Irudayaraj

Open access · greenAbstract readReview
In one paragraph

Review in Molecular pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
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    Review
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  14. Photobiomodulation at 830 nm with 5 J/cmLasers in medical science · 2026
    Article
  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiaoxue HanDepartment of Bioengineering, University of Illinois at Urbana-Champaign, 1102 Everitt Lab, 1406 W. Green St., Urbana, Illinois 61801, United States.
Leah Suyeon JuDepartment of Bioengineering, University of Illinois at Urbana-Champaign, 1102 Everitt Lab, 1406 W. Green St., Urbana, Illinois 61801, United States.
Joseph IrudayarajDepartment of Bioengineering, University of Illinois at Urbana-Champaign, 1102 Everitt Lab, 1406 W. Green St., Urbana, Illinois 61801, United States.ORCID 0000-0002-0630-1520
Carle Foundation Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen is a critical factor that can regulate the wound healing processes such as skin cell proliferation, granulation, re-epithelialization, angiogenesis, and tissue regeneration. However, hypoxia, a common occurrence in the wound bed, can impede normal healing processes. To enhance wound healing, oxygenation strategies that could effectively increase wound oxygen levels are effective. The present review summarizes wound healing stages and the role of hypoxia in wound healing and overviews current strategies to incorporate various oxygen delivery or generating materials for wound dressing, including catalase, nanoenzyme, hemoglobin, calcium peroxide, or perfluorocarbon-based materials, in addition to photosynthetic bacteria and hyperbaric oxygen therapy. Mechanism of action, oxygenation efficacy, and potential benefits and drawbacks of these dressings are also discussed. We conclude by highlighting the importance of design optimization in wound dressings to address the clinical needs to improve clinical outcomes.

Indexed as

BandagesWound HealingHumansHypoxiaOxygenSkinOxygenbioactive materialshypoxiaoxygenated wound dressingskin repairwound healing

Identifiers

PMID37338289
PMCPMC10324602
OpenAlexW4381309550

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.