ArticlemSphere2023
Longitudinal and quantitative fecal shedding dynamics of SARS-CoV-2, pepper mild mottle virus, and crAssphage.
Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed.
- Real-time estimation of pathogen transmission dynamics from wastewater.Nature communications · 2026Article
- Article
- Revealing the hidden burden: wastewater-based epidemiology for underreported and emerging infectious diseases in communities.Environmental monitoring and assessment · 2026Review
- Seasonal and spatial variability of PMMoV in tropical urban wastewater-based surveillance: implications for accurate SARS-CoV-2 monitoring in Kampala, Uganda.BMC public health · 2026Article
- Frequency, dynamics, and duration of faecal shedding in SARS-CoV-2-infected individuals, a scoping review.Epidemiology and infection · 2026Article
- Wastewater concentrations of rotavirus RNA are associated with infection and vaccination metrics in the USA.Npj viruses · 2025Article
- Benchmarking Concentration and Extraction Methods for Wastewater-Based Surveillance of Eight Human Respiratory Viruses: Implications for Rapid Application to Novel Pathogens.Environmental science & technology · 2025Article
- Real-time, multi-pathogen wastewater genomic surveillance with Freyja 2.medRxiv : the preprint server for health sciences · 2025Article
- Dynamics of SARS-CoV-2 variants in southwest Ohio municipal wastewater.Environmental science : water research & technology · 2025Article
- Post-recovery viral shedding shapes wastewater-based epidemiological inferences.Communications medicine · 2025Article
- Hydrological and physicochemical parameters associated with SARS-CoV-2 and pepper mild mottle virus wastewater concentrations for a large-combined sewer system.Journal of water and health · 2025Article
- Spatiotemporal Variability of the Pepper Mild Mottle Virus Biomarker in Wastewater.ACS ES&T water · 2025Article
- Epidemiological model can forecast COVID-19 outbreaks from wastewater-based surveillance in rural communities.Water research · 2025Article
- Temporal dynamics of SARS-CoV-2 detection in wastewater and population infection trends in Mexico City.Frontiers in public health · 2025Article
- Influenza virus infection and aerosol shedding kinetics in a controlled human infection model.Journal of virology · 2024Article
- Alterations of the gut microbiome in HIV infection highlight human anelloviruses as potential predictors of immune recovery.Microbiome · 2024Article
- Article
- Dynamic SARS-CoV-2 surveillance model combining seroprevalence and wastewater concentrations for post-vaccine disease burden estimates.Communications medicine · 2024Article
- Article
- Wastewater surveillance for bacterial targets: current challenges and future goals.Applied and environmental microbiology · 2024Review
Corrections and comments
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Authors and funding
23 authors.
Funding
Abstract
Wastewater-based epidemiology (WBE) emerged during the coronavirus disease 2019 (COVID-19) pandemic as a scalable and broadly applicable method for community-level monitoring of infectious disease burden. The lack of high-resolution fecal shedding data for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) limits our ability to link WBE measurements to disease burden. In this study, we present longitudinal, quantitative fecal shedding data for SARS-CoV-2 RNA, as well as for the commonly used fecal indicators pepper mild mottle virus (PMMoV) RNA and crAss-like phage (crAssphage) DNA. The shedding trajectories from 48 SARS-CoV-2-infected individuals suggest a highly individualized, dynamic course of SARS-CoV-2 RNA fecal shedding. Of the individuals that provided at least three stool samples spanning more than 14 days, 77% had one or more samples that tested positive for SARS-CoV-2 RNA. We detected PMMoV RNA in at least one sample from all individuals and in 96% (352/367) of samples overall. CrAssphage DNA was detected in at least one sample from 80% (38/48) of individuals and was detected in 48% (179/371) of all samples. The geometric mean concentrations of PMMoV and crAssphage in stool across all individuals were 8.7 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.