Observational studyTherapeutic advances in respiratory disease
Validation of the Rome proposal for severity of acute exacerbation of chronic obstructive pulmonary disease.
Observational study in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Inflammation Levels and the Health Impact of Anti-Inflammatory Diets on Chronic Obstructive Pulmonary Disease: An NHANES Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Derivation and Validation of a New Score for Predicting In-Hospital Mortality in Exacerbations of Chronic Obstructive Pulmonary Disease.Journal of general internal medicine · 2025Article
- Validation Study of Rome Criteria for Assessing COPD Exacerbation Severity and Predicting Clinical Outcomes: Turkish Thoracic Society COPD Assembly.International journal of chronic obstructive pulmonary disease · 2025Article
- Stability, variability, and treatment implications of the blood eosinophil count in Korean patients with chronic obstructive pulmonary disease.The Korean journal of internal medicine · 2025Article
- Recommendations for Improving Discharge-Related Care Following a COPD Exacerbation: An Expert Panel Consensus with Emphasis on Low- and Middle-Income Countries.International journal of chronic obstructive pulmonary disease · 2025Article
- Differential decline of lung function in COPD patients according to structural abnormality in chest CT.Heliyon · 2024Article
- Validation of the Rome Severity Classification of Chronic Obstructive Pulmonary Disease Exacerbation: A Multicenter Cohort Study.International journal of chronic obstructive pulmonary disease · 2024Article
- Vitamin D supplementation may be beneficial in improving the prognosis of patients with chronic obstructive pulmonary disease in the intensive care unit: a retrospective study.Frontiers in medicine · 2024Article
- Delphi Consensus on the Management of COPD Exacerbation Syndrome in Inpatient and Outpatient Settings.Open respiratory archivesArticle
- Advancing towards personalized medicine: Practical specifications for management of treatable traits in patients with COPD exacerbations.Therapeutic advances in respiratory diseaseReview
- The EXACERBANTES Study (Open respiratory archivesArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Rome proposal provides an objective assessment tool for severity of acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) but requires validation.
objectivesWe aimed to evaluate the predictive performance of the Rome proposal in patients with AE-COPD.
designThis observational study assessed the patients who visited the emergency room (ER) or were hospitalized due to AE-COPD between January 2010 and December 2020.
methodsWe compared the performance of the Rome Proposal with that of the DECAF score or GesEPOC 2021 criteria in predicting intensive care unit (ICU) admission, need for non-invasive ventilation (NIV) or invasive mechanical ventilation (IMV), and in-hospital mortality.
resultsA total of 740 events of ER visit or hospitalization due to AE-COPD were reviewed and classified into mild (30.9%), moderate (58.6%), or severe (10.4%) group according to the Rome proposal. The severe group had a higher rate of ICU admission, required more NIV or IMV, and had a higher in-hospital mortality than the mild and moderate groups. The predictive performance of the Rome proposal was significantly better for ICU admission [area under the receiver operating characteristic curve (AU-ROC) = 0.850
conclusionExternal validation of the Rome Proposal in Korean patients demonstrated excellent performance for ICU admission and need for NIV or IMV and an acceptable performance for in-hospital mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.