Evidence map›Paper›PMID 37338125›Full record

ArticleProtein science : a publication of the Protein Society2023

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.

Antoine Gedeon, Nour Ayoub, Sébastien Brûlé, Bertrand Raynal, Gouzel Karimova, Muriel Gelin, Ariel Mechaly, Ahmed Haouz, Gilles Labesse, Hélène Munier-Lehmann

Open access · greenAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Structural basis ofbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. A journey into the regulatory secrets of theFrontiers in pharmacology · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Antoine GedeonInstitut Pasteur, Université Paris Cité, Unité de Chimie et Biocatalyse, CNRS UMR3523, Paris, France.ORCID 0000-0003-0301-8786
Nour AyoubInstitut Pasteur, Université Paris Cité, Unité de Chimie et Biocatalyse, CNRS UMR3523, Paris, France.
Sébastien BrûléInstitut Pasteur, Université Paris Cité, Plate-Forme de Biophysique Moléculaire, C2RT, CNRS UMR3528, Paris, France.
Bertrand RaynalInstitut Pasteur, Université Paris Cité, Plate-Forme de Biophysique Moléculaire, C2RT, CNRS UMR3528, Paris, France.
Gouzel KarimovaInstitut Pasteur, Université Paris Cité, Unité de Biochimie des Interactions Macromoléculaires, CNRS UMR3528, Paris, France.
Muriel GelinCentre de Biologie Structurale, Université Montpellier, INSERM, CNRS, Montpellier, France.
Ariel MechalyInstitut Pasteur, Université Paris Cité, Plate-Forme de Cristallographie, C2RT, CNRS UMR3528, Paris, France.
Ahmed HaouzInstitut Pasteur, Université Paris Cité, Plate-Forme de Cristallographie, C2RT, CNRS UMR3528, Paris, France.ORCID 0000-0003-1196-1635
Gilles LabesseCentre de Biologie Structurale, Université Montpellier, INSERM, CNRS, Montpellier, France.
Hélène Munier-LehmannInstitut Pasteur, Université Paris Cité, Unité de Chimie et Biocatalyse, CNRS UMR3523, Paris, France.ORCID 0000-0001-7579-8561
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inosine 5'-monophosphate (IMP) dehydrogenase (IMPDH) is an ubiquitous enzyme that catalyzes the NAD

Indexed as

Adenosine TriphosphateIMP DehydrogenaseBacteriaInosineAdenosine TriphosphateIMP DehydrogenaseInosineallosteryBateman domainenzymologyIMPDHintegrative structural biologypurine nucleotide biosynthesisquaternary structurestructure-function relationship

Identifiers

PMID37338125
PMCPMC10357500
OpenAlexW4381308999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.