ArticleBMC psychiatry2023
Relationship between alexithymia, loneliness, resilience and non-suicidal self-injury in adolescents with depression: a multi-center study.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 4 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- A meta-analysis of influencing factors of non-suicidal self-injury behavior in adolescents with depression.Frontiers in psychiatry · 2026Pooled it
- Resilience revisited: a systematic review and synthesis of Non-Suicidal Self-Injury (NSSI) and its relation with resilience.BMC psychiatry · 2025Pooled it
- The effect of alexithymia on depression: evidence from meta-analysis.Frontiers in psychology · 2025Pooled it
- A meta-analysis on the lifetime and period prevalence of self-injury among adolescents with depression.Frontiers in public health · 2024Pooled it
- Intermittent theta burst stimulation for non-suicidal self-injury in adolescents with major depressive disorder: a randomized, sham-controlled trial.Molecular psychiatry · 2026Trial
- Longitudinal Relationship between Shame, Loneliness, and Nonsuicidal Self-injury Among Chinese Adolescents.Research on child and adolescent psychopathology · 2026Article
- Beyond Emotion Regulation Difficulties: a Cross-National, Cross-Sectional Study of Strengths-Based Psychological Predictors of Self-Injury Among University Students.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Non-Suicidal Self-Injury in Adolescents With Major Depressive Disorder: The Role of Beta-Endorphin, Psychological Pain, and Anhedonia.Alpha psychiatry · 2026Article
- Associational pathway analyses of depression and impulsivity in the relationship between internet addiction and non-suicidal self-injury among adolescents: a cross-sectional case-control study.Annals of general psychiatry · 2026Article
- Altered functional brain network in adolescents with non-suicidal self-injury: a resting-state EEG study.BMC psychiatry · 2026Article
- Alexithymia and self-harm in depressed adolescents: the mediating role of resting-state functional connectivity of the ventral hippocampal-fusiform gyrus.Annals of general psychiatry · 2026Article
- Multifactorial associations of non-suicidal self-injury among adolescents with depression: a network analytic perspective.BMC psychology · 2026Article
- Attention Deficit Hyperactivity Disorder (ADHD) and Self-harm in Chinese Children and Adolescents: A Mediation by Resilience.Journal of autism and developmental disorders · 2026Article
- Emotion Regulation Difficulties as a Statistical Mediator of the Association Between Alexithymia and Coping Strategies in Adolescents.Children (Basel, Switzerland) · 2026Article
- Internet addiction and internet gaming disorder levels as predictors of alexithymia traits among university students.Discover mental health · 2026Article
- Psychological resilience partially mediates the relationship between negative life events and suicidal ideation in Chinese adolescents.Frontiers in psychiatry · 2026Article
- Loneliness in adolescents and youth with bipolar disorder: a scoping review.Frontiers in psychiatry · 2026Review
- Research progress on the characteristic features of non-suicidal self-injury addiction, neuroimaging correlates, and evidence-based interventions in adolescents.Frontiers in psychology · 2026Review
- The relationship between alexithymia, emotion regulation, psychological resilience, and self-management behaviors in kidney transplant recipients: a multicenter structural equation modeling study.Frontiers in psychiatry · 2026Article
- Stressful life events and non-suicidal self-injury among college students: chain mediating effect analysis of resilience and emotion dysregulation.BMC public health · 2025Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNon-suicidal self-injury (NSSI) behaviors are prevalent in adolescents and have adverse effects on physical and mental health. However, little is known about the relationship between NSSI and alexithymia, or the underlying mechanisms that could explain this relationship. This study aimed to elucidate the current status of NSSI in adolescent depression, and analyze the relationship between alexithymia, loneliness, resilience, and adolescent depression with NSSI, so as to provide a theoretical basis for psychotherapeutic interventions.
methodThe study sample involved inpatients and outpatients from 12 hospitals across China and adolescents with depression who met the DSM-5 diagnostic criteria for depression episode. The following scales were used: The Functional Assessment of Self-Mutilation, Toronto Alexithymia Scale, UCLA Loneliness Scale, and Connor Davidson Resilience Scale.
resultsThe detection rate of NSSI in adolescents with depression from 2021.01.01-2022.01.01 was 76.06% (1782/2343). Spearman's correlation analysis revealed a significant correlation between alexithymia, loneliness, resilience and NSSI in depressed adolescents, and the results of the non-parametric test showed that the differences between the two groups for each factor were statistically significant. Binary logistic regression results showed that alexithymia (B = 0.023, p = 0.003, OR = 1.023, 95% CI: 1.008-1.038) and depression (B = 0.045, p < 0.001, OR = 1.046, 95% CI: 1.026-1.066) are risk factors for NSSI, resilience (B = - 0.052, p < 0.001, OR = 0.949, 95% CI: 0.935 - 0.964) is a protective factor for NSSI. Alexithymia directly predicted NSSI and also indirectly influenced NSSI through the mediated effect of resilience. Loneliness moderates the first half of the path of this mediated model.
conclusionThe present study confirms a moderated mediation effect: Alexithymia can have an impact on NSSI behaviors in depressed adolescents through the mediating role of resilience. Loneliness, as a moderating variable, moderated the first half of the pathway of the mediating model. We discuss perspectives for future research and interventions based on the findings of the study.
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