Evidence map›Paper›PMID 37337138›Full record

ArticleBMC geriatrics2023

Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study.

Asmaa Abdelbary, Rasha Kaddoura, Sara Al Balushi, Shiema Ahmed, Richard Galvez, Afif Ahmed, Abdulqadir J Nashwan, Shaikha Alnaimi, Moza Al Hail, Salah Elbdri

Abstract read
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Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Asmaa AbdelbaryPharmacy Department, Community and Home Health Services, Hamad Medical Corporation, Doha, Qatar.
Rasha KaddouraPharmacy Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Sara Al BalushiPharmacy Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Shiema AhmedPharmacy Department, Communicable Disease Center, Hamad Medical Corporation, Doha, Qatar.
Richard GalvezPharmacy Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Afif AhmedCorporate Pharmacy Department, Hamad Medical Corporation, Doha, Qatar.
Abdulqadir J NashwanNursing Department, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar. anashwan@hamad.qa.
Shaikha AlnaimiCorporate Pharmacy Department, Hamad Medical Corporation, Doha, Qatar.
Moza Al HailCorporate Pharmacy Department, Hamad Medical Corporation, Doha, Qatar.
Salah ElbdriCardiology Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe likelihood of elderly patients with heart failure (HF) being readmitted to the hospital is higher if they have a higher medication regimen complexity index (MRCI) compared to those with a lower MRCI. The objective of this study was to investigate whether there is a correlation between the MRCI score and the frequency of hospital readmissions (30-day, 90-day, and 1-year) among elderly patients with HF.

methodsIn this single-center retrospective cohort study, MRCI scores were calculated using a well-established tool. Patients were categorized into high (≥ 15) or low (< 15) MRCI score groups. The primary outcome examined the association between MRCI scores and 30-day hospital readmission rates. Secondary outcomes included the relationships between MRCI scores and 90-day readmission, one-year readmission, and mortality rates. Multivariate logistic regression was employed to assess the 30- and 90-day readmission rates, while Kaplan-Meier analysis was utilized to plot mortality.

resultsA total of 150 patients were included. The mean MRCI score for all patients was 33.43. 90% of patients had a high score. There was no link between a high MCRI score and a high 30-day readmission rate (OR 1.02; 95% CI 0.99-1.05; p < 0.13). A high MCRI score was associated with an initial significant increase in the 90-day readmission rate (odd ratio, 1.03; 95% CI, 1.00-1.07; p < 0.022), but not after adjusting for independent factors (odd ratio, 0.99; 95% CI, 0.95-1.03; p < 0.487). There was no significant difference between high and low MRCI scores in their one-year readmission rate.

conclusionThe study's results indicate that there is no correlation between a higher MRCI score and the rates of hospital readmission or mortality among elderly patients with HF. Therefore, it can be concluded that the medication regimen complexity index does not appear to be a significant predictor of hospital readmission or mortality in this population.

Indexed as

Heart FailurePatient ReadmissionAgedHumansLogistic ModelsPolypharmacyRetrospective StudiesElderlyHeart failureMedication regimen complexityPolypharmacy

Identifiers

PMID37337138
PMCPMC10278269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.